Usutani S, Nishiyama K, Sato I, Matsuura K, Sawada Y, Kawabata T, Hosokawa Y, Izumi S
Sangyo Igaku. 1979 Jan;21(1):21-8. doi: 10.1539/joh1959.21.21.
Special physical examinations were made in order to find out the actual status of damages to health that had broken out in a factory collecting V2O5 from iron sand; and the following results were found: 1. Pharyngitis and bronchitis were found in 25% of the workers exposed to vanadium, but neither pneumonia nor hepatitis was observed. 2. Among the subjective and objective symptoms, respiratory irritation and discoloration of the tongue were frequent. 3. Black spot-like pigmentations gathering in a zonal form 1-2 mm wide in the transitional part and oral mucosa of the upper lip were found. Prevalence rate of this sign was 14.3% in the workers exposed to vanadium. 4. The mean valus of total serum protein and the serum cholesterol in the exposed workers were lower than those in the controls. The difference in the values between both groups is statistically significant. 5. Both the mean values of vanadium concentrations in vurine and its creatinine ratios in the exposed workers were twice to three times those in the controls; however, these parameters decreased to about one third in two months by improving the health and environmental control-measures. 6. Draft items to be checked in special physical examinations of workers handling vanadium have been proposed.
为查明一家从铁砂中收集五氧化二钒的工厂爆发的健康损害实际状况，进行了专项体格检查，结果如下：1. 在接触钒的工人中，25%发现患有咽炎和支气管炎，但未观察到肺炎和肝炎。2. 在主观和客观症状中，呼吸道刺激和舌头变色较为常见。3. 在上唇过渡部位和口腔黏膜发现有呈带状聚集的1 - 2毫米宽的黑斑样色素沉着。接触钒的工人中该体征的患病率为14.3%。4. 接触组工人的血清总蛋白和血清胆固醇均值低于对照组。两组数值差异具有统计学意义。5. 接触组工人尿液中钒浓度及其与肌酐的比值均值是对照组的两到三倍；然而，通过改善健康和环境控制措施，这些参数在两个月内降至约三分之一。6. 提出了钒作业工人专项体格检查中待检查的项目草案。
