Kiviluoto M, Räsänen O, Rinne A, Rissanen M
Scand J Work Environ Health. 1979 Mar;5(1):50-8. doi: 10.5271/sjweh.2666.
An epidemiologic cross-sectional case-history study on the injurious effects of vanadium was carried out among the workers of a vanadium factory. The upper respiratory tract of 63 male workers exposed to vanadium dust was examined macroscopically and microscopically, and the findings were compared with those of a reference group of workers who were exposed to inert dust only. The groups compared were of similar ages and had similar smoking habits. Nasal smears and sputum cells were studied microscopically, and biopsies for histological study were taken from the nasal mucosa. The biopsies from the vanadium workers showed a significant increase in the number of plasma and round cells, and the histological picture was almost characteristic. There were no increased numbers of secretion eosinophils or other signs indicative of allergic inflammation.
在一家钒厂的工人中开展了一项关于钒损伤效应的流行病学横断面病例史研究。对63名接触钒尘的男性工人的上呼吸道进行了宏观和微观检查，并将结果与仅接触惰性粉尘的工人对照组进行了比较。所比较的两组年龄相似且吸烟习惯相近。对鼻涂片和痰液细胞进行了显微镜检查，并从鼻黏膜取活检组织进行组织学研究。钒作业工人的活检组织显示浆细胞和圆形细胞数量显著增加，组织学表现几乎具有特征性。分泌性嗜酸性粒细胞数量没有增加，也没有其他提示过敏性炎症的迹象。
