刺激心脏交感神经传出纤维对犬心脏变时性和变力性的影响。
Chronotropic and inotropic effects on the dog heart of stimulating the efferent cardiac sympathetic nerves.
作者信息
Furnival C M, Linden R J, Snow H M
出版信息
J Physiol. 1973 Apr;230(1):137-53. doi: 10.1113/jphysiol.1973.sp010179.
Abstract
- The chronotropic and inotropic responses of the dog heart to stimulation of the ansae subclaviae were studied.2. The maximum rate of rise of pressure in the left ventricle (dP/dt max) was used as an index of the inotropic changes.3. In experiments in which the secondary inotropic effects of changes in heart rate and blood pressure were prevented it was shown that, using stimuli which produced the same chronotropic response, stimulation of the left ansa subclavia resulted in an inotropic change which was about eight times greater than that which resulted from stimulation of the right ansa subclavia.4. In experiments in which heart rate and blood pressure were allowed to change freely it was shown that the secondary inotropic effects of changes in blood pressure and heart rate amounted to about 70% of the total inotropic change when the right ansa subclavia was stimulated and about 20% of the total change when the left ansa subclavia was stimulated.
摘要
研究了犬心脏对锁骨下袢刺激的变时性和变力性反应。
左心室压力上升的最大速率（dP/dt max）被用作变力性变化的指标。
在防止心率和血压变化的继发性变力性效应的实验中表明，使用产生相同变时性反应的刺激，刺激左锁骨下袢所导致的变力性变化比刺激右锁骨下袢所导致的变力性变化大约大八倍。
在允许心率和血压自由变化的实验中表明，刺激右锁骨下袢时，血压和心率变化的继发性变力性效应约占总变力性变化的70%，而刺激左锁骨下袢时约占总变化的20%。
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