Littler W A, Honour A J, Sleight P
Br Med J. 1973 May 5;2(5861):273-7. doi: 10.1136/bmj.2.5861.273.
Direct arterial pressure and electrocardiogram have been measured continuously over a period of 24 hours in 15 patients. Observations have been made on the behaviour of these variables during 30 separate episodes of motor car driving. The patients were divided into three groups: (1) five normotensive subjects, (2) five patients with essential hypertension who were not receiving therapy, and (3) five patients with angina pectoris who were either normotensive or hypertensive.In all but one subject, apart from variable changes in heart rate, no significant arrhythmias or S-T segment changes were observed in the electrocardiogram. The arterial pressure remained remarkably stable throughout the driving period in all three groups and there was no significant difference between the levels of blood pressure at the beginning and end of a journey. There were short periods of raised arterial pressure during driving related to such episodes as overtaking, but these quickly returned to baseline levels. Two patients experienced anginal pain during driving.It is concluded that motor car driving does not have such a pronounced effect on the blood pressure as might have been thought.
对15名患者连续24小时测量其直接动脉压和心电图。在30次单独的汽车驾驶过程中对这些变量的变化进行了观察。患者被分为三组：（1）5名血压正常的受试者，（2）5名未接受治疗的原发性高血压患者，（3）5名患有心绞痛且血压正常或高血压的患者。除一名受试者外，在所有受试者中，除心率有变化外，心电图中未观察到明显的心律失常或ST段变化。在所有三组中，整个驾驶期间动脉压保持非常稳定，行程开始和结束时的血压水平之间无显著差异。驾驶过程中与超车等情况相关会有短时间的动脉压升高，但这些很快会恢复到基线水平。两名患者在驾驶过程中出现心绞痛。得出的结论是，汽车驾驶对血压的影响并不像人们可能认为的那样显著。
