Molitch M E, Edmonds M, Hendrick J C, Franchimont P, Odell W D
Neuroendocrinology. 1979;29(1):49-53. doi: 10.1159/000122904.
The specificity of the gonadotropin short-loop feedback mechanism was investigated in castrated rabbits by blood sampling from an indwelling jugular venous catheter for follicle-stimulating hormone (FSH) after the intravenous administration of purified human luteinizing hormone (hLH). Although we have previously shown that such hLH administration results in a decrease of rabbit LH, no decrease in rabbit FSH was seen in these experiments. This specificity of LH feedback is compatible with the site of feedback being at the (1) pituitary level or (2) at the hypothalamic level provided two separate LH and FSH releasing factors exist.
通过留置颈静脉导管采血，在阉割兔静脉注射纯化的人促黄体生成素（hLH）后检测促卵泡激素（FSH），以此研究促性腺激素短环反馈机制的特异性。尽管我们之前已表明，这种hLH给药会导致兔促黄体生成素（LH）水平下降，但在这些实验中未观察到兔促卵泡激素（FSH）水平降低。LH反馈的这种特异性与反馈位点在（1）垂体水平或（2）下丘脑水平相符，前提是存在两种独立的促黄体生成素和促卵泡激素释放因子。
