Bucciarelli R L, Eitzman D V
Pediatr Res. 1979 Mar;13(3):178-80. doi: 10.1203/00006450-197903000-00009.
Changes in cerebral blood flow in response to three states of acute acidosis, posthypoxic, lactic acid, and respiratory, were estimated by the microsphere technique. In all three states, the fraction of the systemic blood flow reaching the brain and the rate (ml/min) of blood flow to it increased. The increase in flow was linearly related both to the PaCO2 and to H+. Others have shown the flow rate to increase with hypercapnia, but the increase associated with an increase in hydrogen ion concentration while the PaCO2 was maintained at control levels does not appear to have been observed in mature animals.
采用微球技术评估了急性酸中毒的三种状态（缺氧后、乳酸和呼吸性）下脑血流量的变化。在所有这三种状态下，到达脑的全身血流量的比例及其血流速率（毫升/分钟）均增加。血流量的增加与动脉血二氧化碳分压（PaCO₂）和氢离子（H⁺）均呈线性相关。其他人已表明血流量会随着高碳酸血症而增加，但在成熟动物中似乎尚未观察到在PaCO₂维持在对照水平时，伴随着氢离子浓度增加而出现的血流量增加。
