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K-region and non-K-region metabolism of benzo(a)pyrene by rat liver microsomes.

作者信息

Kinoshita N, Shears B, Gelboin H V

出版信息

Cancer Res. 1973 Aug;33(8):1937-44.

PMID:4720802
Abstract
摘要

相似文献

1
K-region and non-K-region metabolism of benzo(a)pyrene by rat liver microsomes.大鼠肝微粒体对苯并(a)芘的K区和非K区代谢
Cancer Res. 1973 Aug;33(8):1937-44.
2
The direct spectrophotometric observation of benzo(a)pyrene phenol formation by liver microsomes.通过肝微粒体对苯并(a)芘酚形成的直接分光光度法观察。
Cancer Res. 1976 Dec;36(12):4439-43.
3
Inhibition of benzo(a)pyrene and benzo(a)pyrene 7,8-dihydrodiol metabolism by benzo(a)pyrene quinones.苯并(a)芘醌对苯并(a)芘和苯并(a)芘7,8-二氢二醇代谢的抑制作用。
Cancer Res. 1979 Oct;39(10):4123-9.
4
Kinetic determinants of benzo[a]pyrene metabolism to dihydrodiol epoxides by 3-methylcholanthrene-induced rat liver microsomes.3-甲基胆蒽诱导的大鼠肝微粒体将苯并[a]芘代谢为二氢二醇环氧化物的动力学决定因素。
Mol Pharmacol. 1982 Sep;22(2):451-8.
5
Metabolism of benzo(a)pyrene and (-)-trans-7,8-dihydroxy-7,8-dihydrobenzo(a)pyrene by rat liver nuclei and microsomes.大鼠肝细胞核与微粒体对苯并(a)芘及(-)-反式-7,8-二羟基-7,8-二氢苯并(a)芘的代谢
Cancer Res. 1978 May;38(5):1241-5.
6
Modification of benzo(a)pyrene metabolism with microsomes by addition of uridine 5'-diphosphoglucuronic acid.通过添加尿苷5'-二磷酸葡糖醛酸用微粒体修饰苯并(a)芘代谢。
Cancer Res. 1977 Nov;37(11):4125-9.
7
Formation of K-region epoxides as microsomal metabolites of pyrene and benzo(a)pyrene.芘和苯并(a)芘的微粒体代谢产物K-区域环氧化物的形成。
Biochem Pharmacol. 1972 Oct 15;21(20):2713-26. doi: 10.1016/0006-2952(72)90020-2.
8
In vitro metabolism of benzo(a)pyrene by human liver microsomes and lymphocytes.苯并(a)芘在人肝微粒体和淋巴细胞中的体外代谢
Cancer Res. 1975 Dec;35(12):3651-5.
9
Benzo(a)pyrene phenol production by perfused rat liver and its inhibition by ethanol.灌注大鼠肝脏产生苯并(a)芘酚及其受乙醇的抑制作用。
Cancer Res. 1982 May;42(5):1681-5.
10
Immunochemical study on the contributions of two molecular species of microsomal cytochrome P-450 to the metabolism of benzo(a)pyrene by rat liver microsomes.关于微粒体细胞色素P-450的两种分子形式对大鼠肝脏微粒体代谢苯并(a)芘贡献的免疫化学研究。
Cancer Res. 1983 Aug;43(8):3604-8.

引用本文的文献

1
Bioavailability and biotransformation of benzo(a)pyrene in an isolated perfused In situ catfish intestinal preparation.苯并(a)芘在离体灌注原位鲶鱼肠道制剂中的生物利用度和生物转化
Environ Health Perspect. 1998 Mar;106(3):155-66. doi: 10.1289/ehp.98106155.
2
Effects of inducers and epoxide hydrase on the metabolism of benzo(a)pyrene by liver microsomes and a reconstituted system: analysis by high pressure liquid chromatography.诱导剂和环氧化物水解酶对肝脏微粒体及重组系统中苯并(a)芘代谢的影响：高压液相色谱分析
Proc Natl Acad Sci U S A. 1974 Nov;71(11):4356-60. doi: 10.1073/pnas.71.11.4356.
3
The effect of intracellular oxygen on the metabolization of benzo(a)pyrene and benzo(k)fluoranthene. A microspectrofluorometric analysis in single living cells.
Histochemistry. 1974;42(1):75-84. doi: 10.1007/BF00498480.
4
A microspectrofluorometric approach for the study of benzo(a)pyrene and dibenzo(a, h)anthracene metabolization in single living cells.
Histochemistry. 1974;42(1):61-74. doi: 10.1007/BF00498479.
5
On the bioactivation and genotoxic action of fluoranthene.关于荧蒽的生物活化作用和遗传毒性作用。
Arch Toxicol. 1992;66(8):538-45. doi: 10.1007/BF01973383.
6
Enzymatic conversion of benzo(a)pyrene leading predominantly to the diol-epoxide r-7,t-8-dihydroxy-t-9,10-oxy-7,8,9,10-tetrahydrobenzo(a)pyrene through a single enantiomer of r-7, t-8-dihydroxy-7,8-dihydrobenzo(a)pyrene.苯并(a)芘的酶促转化主要通过单一异构体的r-7,t-8-二羟基-7,8-二氢苯并(a)芘生成二醇环氧化物r-7,t-8-二羟基-t-9,10-氧基-7,8,9,10-四氢苯并(a)芘。
Proc Natl Acad Sci U S A. 1976 Aug;73(8):2594-8. doi: 10.1073/pnas.73.8.2594.
7
Identification of mutagenic metabolites of benzo(a)pyrene in mammalian cells.哺乳动物细胞中苯并(a)芘诱变化谢产物的鉴定。
Proc Natl Acad Sci U S A. 1976 Feb;73(2):607-11. doi: 10.1073/pnas.73.2.607.
8
Position-specific oxygenation of benzo(a)pyrene by different forms of purified cytochrome P-450 from rabbit liver.兔肝中不同形式的纯化细胞色素P-450对苯并(a)芘的位点特异性氧化作用。
Proc Natl Acad Sci U S A. 1975 Oct;72(10):3917-20. doi: 10.1073/pnas.72.10.3917.
9
Binding of diethylstilboestrol to deoxyribonucleic acid by rat liver microsomal fractions in vitro and in mouse foetal cells in culture.己烯雌酚在体外经大鼠肝微粒体组分及在培养的小鼠胎儿细胞中与脱氧核糖核酸的结合
Biochem J. 1976 Sep 15;158(3):643-6. doi: 10.1042/bj1580643.
10
Aryl 4-monooxygenase and cytochrome P-450 in the aorta: possible role in atherosclerosis.主动脉中的芳基4-单加氧酶和细胞色素P-450：在动脉粥样硬化中的可能作用。
Proc Natl Acad Sci U S A. 1976 Oct;73(10):3723-5. doi: 10.1073/pnas.73.10.3723.