Fakhri O, Hobbs J R
Br J Cancer. 1973 Jul;28(1):1-5. doi: 10.1038/bjc.1973.64.
Immunotherapy using rat 7s antibodies against plasmacytoma 5563 in C3H mice has been measured carefully. Prior adsorption of antibodies with normal mouse tissues, and supplements of co-optable non-immunized macrophages and lymphocytes enhanced the scope of immunotherapy against established tumours. It is suggested that available co-optable lymphocytes and macrophages are imporant limiting factors in tumour immunotherapy.
在C3H小鼠中,使用针对浆细胞瘤5563的大鼠7s抗体进行免疫疗法已得到仔细测定。用正常小鼠组织预先吸附抗体,以及补充可选用的未免疫巨噬细胞和淋巴细胞,扩大了针对已形成肿瘤的免疫疗法范围。有人提出,可用的可选用淋巴细胞和巨噬细胞是肿瘤免疫疗法中的重要限制因素。