大鼠穹窿下器传出投射切断后出现烦渴并消除了血管紧张素诱导的饮水行为。
Polydipsia and abolition of angiotensin-induced drinking after transections of subfornical organ efferent projections in the rat.
作者信息
Eng R, Miselis R R
出版信息
Brain Res. 1981 Nov 23;225(1):200-6. doi: 10.1016/0006-8993(81)90331-0.
PMID:7296276
Abstract
Rats with transections of subfornical organ (SFO) efferent projections failed to drink to intravenous angiotensin-II (AII) but responded to intracellular dehydration and water deprivation and suppressed drinking when food deprived. However, the transected rats were polydipsic and polyuric. Thus SFO efferent projections mediate AII-induced drinking and may be involved in the regulation of body fluid balance.
摘要
穹窿下器（SFO）传出投射被横断的大鼠不会因静脉注射血管紧张素 II（AII）而饮水，但对细胞内脱水和禁水有反应，并且在食物缺乏时会抑制饮水。然而，横断的大鼠会出现多饮和多尿。因此，SFO 传出投射介导 AII 诱导的饮水，并可能参与体液平衡的调节。
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