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口腔疾病中的食物抗体:复发性口腔溃疡及其他口腔疾病患者血清中食物蛋白抗体的研究

Food antibodies in oral disease: a study of serum antibodies to food proteins in aphthous ulceration and other oral diseases.

作者信息

Thomas H C, Ferguson A, McLennan J G, Mason D K

出版信息

J Clin Pathol. 1973 May;26(5):371-4. doi: 10.1136/jcp.26.5.371.

Abstract

We have investigated the incidence of antibodies to food antigens in patients with recurrent minor aphthous ulceration and in patients with other oral ulcerative diseases. The incidence of these antibodies was the same in both groups of patients and was significantly greater than the incidence in a control group of normal people. There was no evidence to support the hypothesis that aphthous ulceration is primarily due to hypersensitivity to food antigens. The factors which might contribute to the absorption of antigenic molecules from the mouth and to the increased immune response in patients with oral disease have been considered.

摘要

我们调查了复发性轻型阿弗他溃疡患者以及其他口腔溃疡性疾病患者体内食物抗原抗体的发生率。这两组患者中这些抗体的发生率相同,且显著高于正常对照组人群的发生率。没有证据支持阿弗他溃疡主要是由于对食物抗原过敏的假说。我们已经考虑了可能导致口腔内抗原分子吸收以及口腔疾病患者免疫反应增强的因素。

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本文引用的文献

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Serum precipitins to milk, gluten and rice in tropical sprue.
Johns Hopkins Med J. 1967 May;120(5):310-6.
9
Characterization of mucosal antibodies in recurrent aphthous ulceration and Behcet's syndrome.
Arch Oral Biol. 1969 Jul;14(7):843-53. doi: 10.1016/0003-9969(69)90174-5.

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