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乳糜泻伴复发性口疮

Coeliac disease associated with recurrent aphthae.

作者信息

Ferguson M M, Wray D, Carmichael H A, Russell R I, Lee F D

出版信息

Gut. 1980 Mar;21(3):223-6. doi: 10.1136/gut.21.3.223.

Abstract

Fifty patients presenting sequentially with a history of recurrent aphthae were investigated for evidence of nutritional deficiencies and coeliac disease. In the group, two patients were found to have coeliac disease and their recurrent aphthae cleared soon after starting a gluten free diet. This study confirms the presence of an increased prevalence of nutritional deficiency and of coeliac disease in aphthous patients. However, it is recommended that jejunal biopsy be carried out in these cases only where there is evidence of malabsorption.

摘要

对50例有复发性口疮病史的患者进行了营养缺乏和乳糜泻证据的调查。在该组中,发现2例患有乳糜泻,他们在开始无麸质饮食后,复发性口疮很快就痊愈了。这项研究证实了口疮患者中营养缺乏和乳糜泻的患病率增加。然而,建议仅在有吸收不良证据的情况下对这些病例进行空肠活检。

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本文引用的文献

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Enterocyte in coeliac disease. 1.乳糜泻中的肠上皮细胞。1.
Br Med J. 1970 Sep 26;3(5725):725-31. doi: 10.1136/bmj.3.5725.725.
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An immunological study of wheat gluten proteins and derivatives.
Arch Biochem Biophys. 1966 Nov;117(2):239-47. doi: 10.1016/0003-9861(66)90408-5.
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Precipitins to aqueous extracts of flour in coeliac disease.
Lancet. 1970 Jan 31;1(7640):251-2. doi: 10.1016/s0140-6736(70)90624-0.

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