桥本甲状腺炎中的细胞毒性淋巴细胞。一种使用涂有甲状腺球蛋白的51铬标记鸡红细胞的体外检测系统。
Cytotoxic lymphocytes in Hashimoto thyroiditis. An in vitro assay system using 51 Cr-labelled chicken red blood cells coated with thyroglobulin.
作者信息
Calder B A, Penhale W J, Barnes E W, Irvine W J
出版信息
Clin Exp Immunol. 1973 May;14(1):19-23.
Abstract
An method is described to detect lymphocytes in patients with Hashimoto thyroiditis that are cytotoxic to thyroglobulin-coated chicken red blood cells. Using this technique, the cytotoxic index of lymphocytes from patients with Hashimoto thyroiditis was 25·46±3·81 (SEM), which is significantly different from that obtained with lymphocytes from control subjects, 6·28±0·80.
摘要
描述了一种检测桥本甲状腺炎患者中对甲状腺球蛋白包被的鸡红细胞具有细胞毒性的淋巴细胞的方法。使用该技术，桥本甲状腺炎患者淋巴细胞的细胞毒性指数为25.46±3.81（标准误），这与对照组受试者淋巴细胞的细胞毒性指数6.28±0.80有显著差异。
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本文引用的文献
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Human thyroglobulin and thyroid extract as specific stimulators of sensitized lymphocytes.
J Clin Endocrinol Metab. 1971 Jan;32(1):115-6. doi: 10.1210/jcem-32-1-115.
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