2,3-二氢-2,3-二羟基黄曲霉毒素B1：仓鼠和大鼠肝脏微粒体在体外形成的RNA-黄曲霉毒素B1加合物的酸水解产物。 - Suppr

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2,3-Dihydro-2,3-dihydroxy-aflatoxin B1: an acid hydrolysis product of an RNA-aflatoxin B1 adduct formed by hamster and rat liver microsomes in vitro.

作者信息

Swenson D H, Miller J A, Miller E C

出版信息

Biochem Biophys Res Commun. 1973 Aug 21;53(4):1260-7. doi: 10.1016/0006-291x(73)90601-3.

DOI:10.1016/0006-291x(73)90601-3

PMID:4748819

Abstract

摘要

相似文献

2,3-Dihydro-2,3-dihydroxy-aflatoxin B1: an acid hydrolysis product of an RNA-aflatoxin B1 adduct formed by hamster and rat liver microsomes in vitro.2,3-二氢-2,3-二羟基黄曲霉毒素B1：仓鼠和大鼠肝脏微粒体在体外形成的RNA-黄曲霉毒素B1加合物的酸水解产物。

Biochem Biophys Res Commun. 1973 Aug 21;53(4):1260-7. doi: 10.1016/0006-291x(73)90601-3.

Chemical evidence for the formation of a reactive aflatoxin B1 metabolite, by hamster liver microsomes.仓鼠肝脏微粒体形成活性黄曲霉毒素B1代谢物的化学证据。

FEBS Lett. 1973 Nov 1;36(3):261-4. doi: 10.1016/0014-5793(73)80386-2.

Aflatoxin B1-2,3-oxide: evidence for its formation in rat liver in vivo and by human liver microsomes in vitro.黄曲霉毒素B1 - 2,3 - 环氧化物：其在大鼠肝脏体内形成及人肝脏微粒体体外形成的证据。

Biochem Biophys Res Commun. 1974 Oct 8;60(3):1036-43. doi: 10.1016/0006-291x(74)90417-3.

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro.黄曲霉毒素B1体外形成的主要DNA加合物的结构鉴定。

Proc Natl Acad Sci U S A. 1977 May;74(5):1870-4. doi: 10.1073/pnas.74.5.1870.

2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo.2,3-二氢-2-（鸟嘌呤-7-基）-3-羟基黄曲霉毒素B1，是在肝微粒体介导的反应以及大鼠肝脏体内形成的黄曲霉毒素B1-DNA或-核糖体RNA加合物的主要酸水解产物。

Cancer Res. 1977 Dec;37(12):4430-8.

Microsome-dependent binding of aflatoxin B1 to DNA, RNA, polyribonucleotides and protein in vitro.体外微粒体依赖性黄曲霉毒素B1与DNA、RNA、多聚核糖核苷酸及蛋白质的结合

Chem Biol Interact. 1973 Feb;6(2):125-9. doi: 10.1016/0009-2797(73)90079-3.

The formation of 2,3-dihydro-2,3-dihydroxy aflatoxin B1 by the metabolism of aflatoxin B1 in vitro by rat liver microsomes.黄曲霉毒素B1在大鼠肝脏微粒体体外代谢过程中形成2,3-二氢-2,3-二羟基黄曲霉毒素B1 。

FEBS Lett. 1979 May 15;101(2):382-6. doi: 10.1016/0014-5793(79)81049-2.

Reduced nicotinamide adenine dinucleotide phosphate-dependent formation of 2,3-dihydro-2,3-dihydroxyaflatoxin B1 from aflatoxin B1 by hepatic microsomes.肝微粒体将黄曲霉毒素B1还原为2,3-二氢-2,3-二羟基黄曲霉毒素B1的烟酰胺腺嘌呤二核苷酸磷酸依赖性形成过程。

Cancer Res. 1978 Aug;38(8):2424-8.

The formation of 2,3-dihydroxy-2,3-dihydro-aflatoxin B1 by the metabolism of aflatoxin B1 by liver microsomes isolated from certain avian and mammalian species and the possible role of this metabolite in the acute toxicity of aflatoxin B1.从某些禽类和哺乳动物物种中分离出的肝微粒体对黄曲霉毒素B1进行代谢生成2,3 - 二羟基 - 2,3 - 二氢黄曲霉毒素B1，以及该代谢产物在黄曲霉毒素B1急性毒性中可能发挥的作用。

Toxicol Appl Pharmacol. 1981 May;58(3):431-7. doi: 10.1016/0041-008x(81)90095-8.

Oxidative metabolism of aflatoxin B1 by rat liver microsomes in vitro and its effect on lipid peroxidation.黄曲霉毒素B1在大鼠肝脏微粒体中的体外氧化代谢及其对脂质过氧化的影响。

Res Commun Chem Pathol Pharmacol. 1974 Aug;8(4):703-6.

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Dealing with aflatoxin B1 dihydrodiol acute effects: Impact of aflatoxin B1-aldehyde reductase enzyme activity in poultry species tolerant to AFB1 toxic effects.应对黄曲霉毒素 B1 二氢二醇的急性作用：黄曲霉毒素 B1 醛还原酶活性对耐受 AFB1 毒性作用的家禽物种的影响。

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An unusually high production of hepatic aflatoxin B-dihydrodiol, the possible explanation for the high susceptibility of ducks to aflatoxin B.鸭类对黄曲霉毒素 B1 的易感性高，可能是因为其肝脏能异常大量生成黄曲霉毒素 B1 的二氢二醇。

Sci Rep. 2019 May 29;9(1):8010. doi: 10.1038/s41598-019-44515-6.

Aflatoxin B₁⁻Formamidopyrimidine DNA Adducts: Relationships between Structures, Free Energies, and Melting Temperatures.黄曲霉毒素 B₁⁻甲酰胺嘧啶 DNA 加合物：结构、自由能和熔点之间的关系。

Molecules. 2019 Jan 2;24(1):150. doi: 10.3390/molecules24010150.

In vitro microsome-mediated aflatoxin B1-DNA binding and its inhibition by cytosol of various organs of the hamster and quail.体外微粒体介导的黄曲霉毒素B1与DNA结合及其受仓鼠和鹌鹑各器官胞质溶胶的抑制作用。

Mycopathologia. 1995 Nov;132(2):117-9. doi: 10.1007/BF01103784.

In vitro cytochrome P450 monooxygenase and prostaglandin H-synthase mediated aflatoxin B1 biotransformation in guinea pig tissues: effects of beta-naphthoflavone treatment.体外细胞色素P450单加氧酶和前列腺素H合成酶介导豚鼠组织中黄曲霉毒素B1的生物转化：β-萘黄酮处理的影响

Arch Toxicol. 1993;67(6):379-85. doi: 10.1007/BF01977398.

Different tissue responses of mixed function oxidases and detoxifying enzymes to aflatoxin B1 administration in the rat.大鼠体内混合功能氧化酶和解毒酶对黄曲霉毒素B1给药的不同组织反应。

Br J Exp Pathol. 1980 Dec;61(6):611-6.

The metabolism of 8-methoxypsoralen in man.

Eur J Drug Metab Pharmacokinet. 1980;5(2):81-92. doi: 10.1007/BF03189450.

Peliosis hepatis. Its relationship to chronic alcoholism, aflatoxin B1, and carcinogenesis in male Holtzman rats.肝紫癜。其与雄性霍尔茨曼大鼠慢性酒精中毒、黄曲霉毒素B1及致癌作用的关系。

Dig Dis Sci. 1980 Aug;25(8):587-92. doi: 10.1007/BF01318871.

Biological activity and electronic structure of the aflatoxins.黄曲霉毒素的生物活性与电子结构

Br J Cancer. 1974 Jun;29(6):470-6. doi: 10.1038/bjc.1974.99.

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