体外微粒体依赖性黄曲霉毒素B1与DNA、RNA、多聚核糖核苷酸及蛋白质的结合 - Suppr

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Microsome-dependent binding of aflatoxin B1 to DNA, RNA, polyribonucleotides and protein in vitro.

作者信息

Garner R C

出版信息

Chem Biol Interact. 1973 Feb;6(2):125-9. doi: 10.1016/0009-2797(73)90079-3.

DOI:10.1016/0009-2797(73)90079-3

PMID:4698160

Abstract

摘要

相似文献

Microsome-dependent binding of aflatoxin B1 to DNA, RNA, polyribonucleotides and protein in vitro.体外微粒体依赖性黄曲霉毒素B1与DNA、RNA、多聚核糖核苷酸及蛋白质的结合

Chem Biol Interact. 1973 Feb;6(2):125-9. doi: 10.1016/0009-2797(73)90079-3.

2,3-Dihydro-2,3-dihydroxy-aflatoxin B1: an acid hydrolysis product of an RNA-aflatoxin B1 adduct formed by hamster and rat liver microsomes in vitro.2,3-二氢-2,3-二羟基黄曲霉毒素B1：仓鼠和大鼠肝脏微粒体在体外形成的RNA-黄曲霉毒素B1加合物的酸水解产物。

Biochem Biophys Res Commun. 1973 Aug 21;53(4):1260-7. doi: 10.1016/0006-291x(73)90601-3.

In vitro metabolic conversion of aflatoxins and benzo(alpha)pyrene to nucleic acid-binding metabolites.黄曲霉毒素和苯并（α）芘在体外代谢转化为核酸结合代谢物。

Cancer Res. 1975 Feb;35(2):382-9.

On the binding of aflatoxin B 1 and its metabolites to hepatic microsomes.关于黄曲霉毒素B1及其代谢产物与肝微粒体的结合

Biochem Biophys Res Commun. 1973 Feb 5;50(3):649-55. doi: 10.1016/0006-291x(73)91293-x.

Modulation of microsome-mediated aflatoxin B1 binding to exogenous and endogenous DNA by cytosolic glutathione S-transferases in rat and hamster livers.大鼠和仓鼠肝脏中胞质谷胱甘肽S-转移酶对微粒体介导的黄曲霉毒素B1与外源性和内源性DNA结合的调节作用。

Carcinogenesis. 1984 Feb;5(2):269-76. doi: 10.1093/carcin/5.2.269.

Microsome-dependent binding of benzo(alpha)pyrene and aflatoxin B1 to DNA, and benzo(alpha)pyrene binding to aflatoxin-conjugated DNA.微粒体介导的苯并（α）芘和黄曲霉毒素B1与DNA的结合，以及苯并（α）芘与黄曲霉毒素共轭DNA的结合。

Cancer Res. 1974 Dec;34(12):3289-95.

Structural identification of the major DNA adduct formed by aflatoxin B1 in vitro.黄曲霉毒素B1体外形成的主要DNA加合物的结构鉴定。

Proc Natl Acad Sci U S A. 1977 May;74(5):1870-4. doi: 10.1073/pnas.74.5.1870.

Factors modulating the formation of DNA adduct by aflatoxin B1 in vitro.体外黄曲霉毒素B1调节DNA加合物形成的因素。

Carcinogenesis. 1984 Oct;5(10):1359-62. doi: 10.1093/carcin/5.10.1359.

2,3-Dihydro-2-(guan-7-yl)-3-hydroxy-aflatoxin B1, a major acid hydrolysis product of aflatoxin B1-DNA or -ribosomal RNA adducts formed in hepatic microsome-mediated reactions and in rat liver in vivo.2,3-二氢-2-（鸟嘌呤-7-基）-3-羟基黄曲霉毒素B1，是在肝微粒体介导的反应以及大鼠肝脏体内形成的黄曲霉毒素B1-DNA或-核糖体RNA加合物的主要酸水解产物。

Cancer Res. 1977 Dec;37(12):4430-8.

Inhibition of microsome-mediated binding of aflatoxin B1 to DNA by glutathione S-transferase.谷胱甘肽S-转移酶对微粒体介导的黄曲霉毒素B1与DNA结合的抑制作用。

Cancer Lett. 1980 Apr;9(2):143-9. doi: 10.1016/0304-3835(80)90118-4.

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The Evolution of Carcinogenesis.致癌作用的演变

Toxicol Sci. 2018 Oct 1;165(2):272-276. doi: 10.1093/toxsci/kfy184.

In vitro microsome-mediated aflatoxin B1-DNA binding and its inhibition by cytosol of various organs of the hamster and quail.体外微粒体介导的黄曲霉毒素B1与DNA结合及其受仓鼠和鹌鹑各器官胞质溶胶的抑制作用。

Mycopathologia. 1995 Nov;132(2):117-9. doi: 10.1007/BF01103784.

Base substitution mutations induced by metabolically activated aflatoxin B1.由代谢活化的黄曲霉毒素B1诱导的碱基置换突变。

Proc Natl Acad Sci U S A. 1983 May;80(9):2695-8. doi: 10.1073/pnas.80.9.2695.

Mechanism of action of aflatoxin B1 in Bacillus megaterium.黄曲霉毒素B1在巨大芽孢杆菌中的作用机制。

Appl Environ Microbiol. 1985 Apr;49(4):904-7. doi: 10.1128/aem.49.4.904-907.1985.

Mechanism of counteraction of aflatoxin toxicity by thymine and folic acid in Bacillus megaterium.胸腺嘧啶和叶酸对巨大芽孢杆菌中黄曲霉毒素毒性的拮抗机制。

Folia Microbiol (Praha). 1986;31(4):272-6. doi: 10.1007/BF02926950.

Evidence for cytochrome P-450NF, the nifedipine oxidase, being the principal enzyme involved in the bioactivation of aflatoxins in human liver.细胞色素P - 450NF（硝苯地平氧化酶）作为人肝脏中黄曲霉毒素生物活化主要酶的证据。

Proc Natl Acad Sci U S A. 1989 Jan;86(2):462-5. doi: 10.1073/pnas.86.2.462.

Mutagenicity of aflatoxins related to their metabolism and carcinogenic potential.黄曲霉毒素的致突变性与其代谢及致癌潜力相关。

Proc Natl Acad Sci U S A. 1976 Jul;73(7):2241-4. doi: 10.1073/pnas.73.7.2241.

Some high-performance liquid-chromatographic studies of the metabolism of aflatoxins by rat liver microsomal preparations.大鼠肝脏微粒体制剂对黄曲霉毒素代谢的一些高效液相色谱研究。

Biochem J. 1978 Sep 15;174(3):839-51. doi: 10.1042/bj1740839.

Biological activities of mycotoxins.霉菌毒素的生物活性。

Mycopathologia. 1978 Dec 18;65(1-3):29-41. doi: 10.1007/BF00447171.

Identification of the principal aflatoxin B1-DNA adduct formed in vivo in rat liver.大鼠肝脏中体内形成的主要黄曲霉毒素B1-DNA加合物的鉴定。

Proc Natl Acad Sci U S A. 1978 Apr;75(4):1745-9. doi: 10.1073/pnas.75.4.1745.

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