Biochemical aspects of motor neurone disease--Madras pattern.
作者信息
Valmikinathan K, Mascreen M, Meenakshisundaram E, Snehalatha C
出版信息
J Neurol Neurosurg Psychiatry. 1973 Oct;36(5):753-6. doi: 10.1136/jnnp.36.5.753.
Abstract
A detailed study of four cases of MND-Madras has shown a significantly low plasma citrate level in these subjects. Comparison with other related groups of neurological disorders indicates the citrate/pyruvate ratio to be of diagnostic value in MND-Madras. This seems to suggest that the pathophysiology of MND-Madras may centre round altered citrate metabolism.
摘要
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