Bedi J F, Folinsbee L J, Horvath S M, Ebenstein R S
Arch Environ Health. 1979 Jul-Aug;34(4):233-9. doi: 10.1080/00039896.1979.10667405.
Studies of the human health effects of exposure to a combination of ozone and sulfur dioxide have produced somewhat conflicting results; the possibility of a synergistic enhancement of toxicity when the two gases are present simultaneously remains equivocal. We evaluated the effects of 0.40 ppm sulfur dioxide, 0.40 ppm ozone, and the combination of these two under one environmental condition (25 degrees C and 45% relative humidity). Subjects alternately walked and rested during a 2-hr exposure. Subjects exposed to filtered air or to 0.40 ppm sulfur dioxide showed no significant changes in pulmonary function. When exposed to either ozone or ozone plus sulfur dioxide, significant decreases in maximum expiratory flow, forced vital capacity, and inspiratory capacity were observed. There were no significant differences in response between ozone alone and ozone plus sulfur dioxide exposures, thus, in our subjects on synergistic effects were discernible.
关于接触臭氧和二氧化硫组合对人体健康影响的研究结果有些相互矛盾；当两种气体同时存在时，毒性协同增强的可能性仍不明确。我们评估了在一种环境条件（25摄氏度和45%相对湿度）下，0.40 ppm二氧化硫、0.40 ppm臭氧以及这两种气体组合的影响。在2小时的暴露期间，受试者交替行走和休息。暴露于过滤空气或0.40 ppm二氧化硫的受试者肺功能无显著变化。当暴露于臭氧或臭氧加二氧化硫时，观察到最大呼气流量、用力肺活量和吸气量显著下降。单独臭氧暴露和臭氧加二氧化硫暴露之间的反应没有显著差异，因此，在我们的受试者中未发现协同效应。
