Maeda S, Mogi G, Oh M
Arch Otorhinolaryngol. 1979;222(4):247-56. doi: 10.1007/BF01261170.
To explain the developmental process of epithelial cells of true vocal cords, larynges obtained from 42 fetal and 36 developing young rats were examined using scanning and transmission electron microscopies. Although the membranous portion was indistinguishable from the arytenoid portion in the prenatal stage, there was no squamous cell epithelium on the glottis. The lining epithelium of vocal cords in 15, 16, and 17 day fetal rats was composed of cuboidal and columnar cells which had a primary cilium. Immediately after birth the membranous portion of vocal cords became recognizable, and ciliated cells present on vocal cords retrogressed rapidly while nonciliated squamous cells grew and extended. Results of the present study show that epithelial cells of ciliated columnar type covering vocal cords change remarkably to nonciliated squamous cells between prenatal and postnatal stages.
为了解真声带上皮细胞的发育过程，利用扫描电子显微镜和透射电子显微镜对42只胎鼠和36只发育中的幼鼠的喉部进行了检查。虽然在产前阶段膜部与杓状软骨部难以区分，但声门上没有鳞状细胞上皮。15、16和17日龄胎鼠声带的衬里上皮由具有初级纤毛的立方细胞和柱状细胞组成。出生后立即可以识别出声带的膜部，声带上存在的纤毛细胞迅速退化，而非纤毛鳞状细胞则生长并扩展。本研究结果表明，覆盖声带的纤毛柱状上皮细胞在产前和产后阶段之间显著转变为非纤毛鳞状细胞。
