Piller N B, Clodius L
Br J Exp Pathol. 1979 Jun;60(3):328-34.
In an experimental model of chronic lymphoedema in the dog leg it has been shown that the presence of lymphoedema was associated with reduced numbers of macrophages found on subcutaneously implanted coverslips. Total numbers of mononuclear cells were not, however, significantly affected. When expressed as a percentage of the total mononuclear cells attached, the lymphoedematous limbs always had only half those of the corresponding normal limbs. Similarly, the percentage of macrophages with two or more pseudopods on the coverslips in the lymphoedematous limbs was only 1/3 of that for the same morphological criteria in normal limbs. However, when the macrophages with vacuoles were expressed as a percentage of the total macrophages, there was always a higher percentage in the lymphoedematous limbs compared with the corresponding normal ones.
在犬腿部慢性淋巴水肿的实验模型中，已表明淋巴水肿的存在与皮下植入盖玻片上发现的巨噬细胞数量减少有关。然而，单核细胞总数并未受到显著影响。当以附着的单核细胞总数的百分比表示时，淋巴水肿肢体的该比例始终仅为相应正常肢体的一半。同样，淋巴水肿肢体盖玻片上具有两个或更多伪足的巨噬细胞百分比仅为正常肢体相同形态学标准的三分之一。然而，当有液泡的巨噬细胞以占总巨噬细胞的百分比表示时，与相应正常肢体相比，淋巴水肿肢体中的百分比始终更高。
