香豆素对巨噬细胞刺激作用的形态学评估。
A morphological assessment of the stimulatory effect of coumarin on macrophages.
作者信息
Piller N B
出版信息
Br J Exp Pathol. 1978 Feb;59(1):93-6.
Abstract
In examining the migration of macrophages on to subcutaneously implanted coverslips in rats, it was found that coumarin (5-6 benzo-alpha-pyrone) and a preparation (Venalot) containing the former, very significantly increased the total macrophage number as well as the percentage of stimulation on the skin side of the coverslip. For the muscle side, Venalot increased the total numbers and the percentage stimulated while coumarin alone had no effect compared with the control. It remains to be seen whether these stimulated macrophages are also activated.
摘要
在研究大鼠皮下植入盖玻片上巨噬细胞的迁移时发现，香豆素（5 - 6苯并-α-吡喃酮）以及含有香豆素的制剂（维纳洛），能非常显著地增加巨噬细胞总数以及盖玻片皮肤侧的刺激百分比。对于肌肉侧，维纳洛增加了总数和受刺激的百分比，而单独使用香豆素与对照组相比没有效果。这些受刺激的巨噬细胞是否也被激活还有待观察。
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