Kosztolányi G, Jobst K
Biol Neonate. 1979;35(5-6):255-7. doi: 10.1159/000241182.
The effect of acidosis on platelet surface potential was studied in vitro in samples obtained from newborn infants. It was found that acidosis induced by CO2 and lactic acid decreased the electrophoretic mobility of platelets in the presence of plasma. It is suggested that the changed electrokinetic properties of platelets in acidosis may be an additional factor contributing to bleeding manifestations and thrombotic complications often seen in babies with perinatal asphyxia.
在取自新生儿的样本中,于体外研究了酸中毒对血小板表面电位的影响。结果发现,在血浆存在的情况下,由二氧化碳和乳酸诱导的酸中毒会降低血小板的电泳迁移率。有人提出,酸中毒时血小板电动特性的改变可能是导致围产期窒息婴儿常见的出血表现和血栓形成并发症的一个额外因素。