维生素A缺乏对大鼠睾丸和卵巢胆固醇侧链裂解酶活性的影响。
Effect of vitamin A deprivation on the cholesterol side-chain cleavage enzyme activity of testes and ovaries of rats.
作者信息
Jayaram M, Murthy S K, Ganguly J
出版信息
Biochem J. 1973 Sep;136(1):221-3. doi: 10.1042/bj1360221.
Abstract
The cholesterol side-chain cleavage enzyme activity is decreased considerably at the mild stage of vitamin A deficiency in rat testes and ovaries and the decrease in activity becomes more pronounced with progress of deficiency. Supplementation of the deficient rats with retinyl acetate, but not retinoic acid, restores the enzyme activity to normal values. The cholesterol side-chain cleavage enzyme of adrenals is not affected by any of the above treatments.
摘要
在维生素A缺乏的轻度阶段，大鼠睾丸和卵巢中的胆固醇侧链裂解酶活性显著降低，且随着缺乏程度的加重，活性降低变得更加明显。给缺乏维生素A的大鼠补充醋酸视黄酯而非视黄酸，可使该酶活性恢复至正常水平。肾上腺的胆固醇侧链裂解酶不受上述任何处理的影响。
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