Varhaug J E, Svanes K, Søreide O, Skarstein A
Eur Surg Res. 1979;11(1):15-26. doi: 10.1159/000128048.
Partial devascularization of the stomach was performed in cats anesthetized with pentobarbital. The devascularization included all blood vessels along the greater curvature and two of the main branches of the left gastric artery. Gastric mucosal blood flow and cardiac output were determined by means of the microsphere distribution technique. The acid (H+) output from the 30th to the 60th min of pentagastrin stimulation was used as the 'acid response value'. Blood flow and acid secretion were determined before and approximately 2 h after devascularization or sham operation. A marked decrease in acid secretion and mucosal blood flow of the corpus/fundus occurred after devascularization. A high degree of correlation was found between the decrease in acid secretion and the decrease in mucosal blood flow caused by the devascularization. The regression coefficient of acid secretion on mucosal blood flow did not change significantly after devascularization.
对用戊巴比妥麻醉的猫进行胃部分去血管化手术。去血管化包括沿胃大弯的所有血管以及胃左动脉的两个主要分支。采用微球分布技术测定胃黏膜血流量和心输出量。将五肽胃泌素刺激第30至60分钟的酸（H⁺）分泌量用作“酸反应值”。在去血管化或假手术后约2小时前后分别测定血流量和酸分泌。去血管化后胃体/胃底的酸分泌和黏膜血流量显著降低。发现去血管化引起的酸分泌减少与黏膜血流量减少之间存在高度相关性。去血管化后酸分泌对黏膜血流量的回归系数无明显变化。
