Varhaug J E, Svanes K, Lysen L J, Holm P
Eur Surg Res. 1980;12(6):415-27. doi: 10.1159/000128149.
The influence of intragastric pressure (IGP) on gastric blood flow was studied in cats with regional ischemia due to partial gastric devascularization, and in sham-operated cats. IGP was controlled by intragastric installation of saline. Blood flow was determined by means of the microsphere distribution technique. Increment of IGP reduced mucosal and muscularis blood flow in all areas of the stomach, both in sham-operated and devascularized cats. In areas with reduced mucosal blood flow due to devascularization, blood flow became further reduced by IGP to an extremely low flow level. The present results are pertinent to the pathogenesis of early lesser curvature ulcer or necrosis sometimes ll areas of the stomach, both in sham-operated and devascularized cats. In areas with reduced mucosal blood flow due to devascularization, blood flow became further reduced by IGP to an extremely low flow level. The present results are pertinent to the pathogenesis of early lesser curvature ulcer or necrosis sometimes ll areas of the stomach, both in sham-operated and devascularized cats. In areas with reduced mucosal blood flow due to devascularization, blood flow became further reduced by IGP to an extremely low flow level. The present results are pertinent to the pathogenesis of early lesser curvature ulcer or necrosis sometimes occurring after proximal gastric vagotomy in man.
在因部分胃血管离断导致局部缺血的猫和假手术猫中，研究了胃内压（IGP）对胃血流量的影响。通过向胃内注入生理盐水来控制IGP。采用微球分布技术测定血流量。在假手术猫和血管离断猫中，IGP升高均会使胃各部位的黏膜和肌层血流量减少。在因血管离断导致黏膜血流量减少的区域，IGP会使血流量进一步降低至极低水平。本研究结果与在假手术猫和血管离断猫中，胃有时出现的早期小弯侧溃疡或坏死的发病机制相关。在因血管离断导致黏膜血流量减少的区域，IGP会使血流量进一步降低至极低水平。本研究结果与在假手术猫和血管离断猫中，胃有时出现的早期小弯侧溃疡或坏死的发病机制相关。在因血管离断导致黏膜血流量减少的区域，IGP会使血流量进一步降低至极低水平。本研究结果与人类近端胃迷走神经切断术后有时发生的早期小弯侧溃疡或坏死的发病机制相关。
