2-卤代乙醇对α-糜蛋白酶的抑制作用；与2-甲基乙醇和尿素的比较。
Inhibition of alpha-chymotrypsin by 2-halogeno-ethanols; comparisons with 2-methyl-ethanols and urea.
作者信息
Ebina S, Kobayashi T, Nagai Y
出版信息
Experientia. 1979 Aug 15;35(8):1011-2. doi: 10.1007/BF01949911.
PMID:477859
Abstract
2-Halogeno- and 2-methyl-ethanols inhibit alpha-chymotrypsin in the order of their substituted groups: [1] tri- greater than di- greater than mono-, [2] Br- greater than Cl- greater than CH3- greater than F-. The inhibition by the halogeno-ethanols is mediated differently from that by the methyl-ethanols, ethanol, and urea.
摘要
2-卤代乙醇和2-甲基乙醇按其取代基团的顺序抑制α-胰凝乳蛋白酶：[1]三取代大于二取代大于单取代，[2]溴大于氯大于甲基大于氟。卤代乙醇的抑制作用与甲基乙醇、乙醇和尿素的抑制作用介导方式不同。
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