Knippenberger H, Vanselow H, Barth H, Scheffzek H D, Rüttgers H
Geburtshilfe Frauenheilkd. 1979 Aug;39(8):676-81.
In the out-patient department and antenatal clinic 1000 patients were examined for yeast of the genital tract by the nickerson-medium. In 10.3% of the patients the cultures showed yeast. The wet-mount preparation examination under phase contrast microscopy was compared to the nickerson-medi-m culture. Patients with a past history of yeast infections or patients with an intrauterine device showed a statistically significant increase in the rate of yeast vaginitis compared to the control groups. Patients who had antibiotics or were treated with corticosteroids showed a higher incidence of yeast vaginitis than normal controls. Controls had a 9% incidence. The number of cases was too small for statistical analysis. The incidence of yeast vaginitis in patients on combined or sequential oral contraceptives was the same as in the control groups. The pregnant patients and obese patients did not show an increased incidence of yeast. High risk patients for yeast vaginitis are defined in which a culture for yeast is jusitfied. Especially antenatal patients in the last trimestre are a high risk group because of the possibility of neonatal thrush.
在门诊部和产前诊所,使用尼克森培养基对1000名患者进行了生殖道酵母菌检查。10.3%的患者培养物显示有酵母菌。将相差显微镜下的湿片制备检查结果与尼克森培养基培养结果进行了比较。与对照组相比,有酵母菌感染病史的患者或宫内节育器使用者的霉菌性阴道炎发病率有统计学意义的增加。使用抗生素或接受皮质类固醇治疗的患者霉菌性阴道炎发病率高于正常对照组。对照组的发病率为9%。病例数量过少,无法进行统计分析。联合或序贯口服避孕药使用者的霉菌性阴道炎发病率与对照组相同。孕妇和肥胖患者的酵母菌发病率没有增加。确定了霉菌性阴道炎的高危患者群体,对其进行酵母菌培养是合理的。特别是孕晚期的产前患者是高危群体,因为有新生儿鹅口疮的可能性。