Russell M A
Postgrad Med J. 1973 Oct;49(576):684-7. doi: 10.1136/pgmj.49.576.684.
Using multiple samples collected via an indwelling venous cannula changes in blood carboxyhaemoglobin (COHb) were studied in five subjects before, during and up to 2½ hr after smoking. On average the smoking, with inhalation, of one cigarette in 6½ min raised the% COHb by 1·6, compared with 2·2 for 24 min of inhaled cigar smoking and only 0·2 for 20 min of non-inhaled pipe smoking. It is suggested that it may be paradoxically safer to smoke high rather than low nicotine cigarettes as those with a high nicotine content will tend to be inhaled less.
通过留置静脉套管采集多个样本，研究了5名受试者在吸烟前、吸烟期间以及吸烟后长达2个半小时内血液中碳氧血红蛋白（COHb）的变化。平均而言，在6.5分钟内吸一支烟并吸入，会使碳氧血红蛋白百分比升高1.6，相比之下，吸入雪茄24分钟会使其升高2.2，而吸20分钟非吸入式烟斗仅使其升高0.2。有人认为，吸高尼古丁含量而非低尼古丁含量的香烟可能反而更安全，因为尼古丁含量高的香烟往往吸入量较少。
