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吸烟过程中血液碳氧血红蛋白的变化。

Blood carboxyhaemoglobin changes during tobacco smoking.

作者信息

Russell M A

出版信息

Postgrad Med J. 1973 Oct;49(576):684-7. doi: 10.1136/pgmj.49.576.684.

Abstract

Using multiple samples collected via an indwelling venous cannula changes in blood carboxyhaemoglobin (COHb) were studied in five subjects before, during and up to 2½ hr after smoking. On average the smoking, with inhalation, of one cigarette in 6½ min raised the% COHb by 1·6, compared with 2·2 for 24 min of inhaled cigar smoking and only 0·2 for 20 min of non-inhaled pipe smoking. It is suggested that it may be paradoxically safer to smoke high rather than low nicotine cigarettes as those with a high nicotine content will tend to be inhaled less.

摘要

通过留置静脉套管采集多个样本,研究了5名受试者在吸烟前、吸烟期间以及吸烟后长达2个半小时内血液中碳氧血红蛋白(COHb)的变化。平均而言,在6.5分钟内吸一支烟并吸入,会使碳氧血红蛋白百分比升高1.6,相比之下,吸入雪茄24分钟会使其升高2.2,而吸20分钟非吸入式烟斗仅使其升高0.2。有人认为,吸高尼古丁含量而非低尼古丁含量的香烟可能反而更安全,因为尼古丁含量高的香烟往往吸入量较少。

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本文引用的文献

1
Retention of cigarette smoke components in human lungs.香烟烟雾成分在人肺中的留存。
Arch Environ Health. 1968 Nov;17(5):746-8. doi: 10.1080/00039896.1968.10665315.
2
Cigarette dependence. I. Nature and classification.香烟依赖。一、性质与分类。
Br Med J. 1971 May 8;2(5757):330-1. doi: 10.1136/bmj.2.5757.330.
6
Blood lead and carboxyhaemoglobin levels in London taxi drivers.
Lancet. 1972 Aug 12;2(7772):302-3. doi: 10.1016/s0140-6736(72)92907-8.
7
Cigarette smoking and exposure to carbon monoxide.吸烟与接触一氧化碳。
Ann N Y Acad Sci. 1970 Oct 5;174(1):135-47. doi: 10.1111/j.1749-6632.1970.tb49780.x.

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