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Enhancement of carcinoembryonic antigen expression by interferon.

作者信息

Attallah A M, Needy C F, Noguchi P D, Elisberg B L

出版信息

Int J Cancer. 1979 Jul 15;24(1):49-52. doi: 10.1002/ijc.2910240109.

DOI:10.1002/ijc.2910240109
PMID:478691
Abstract

Human interferon decreased DNA but not RNA synthesis in a human colon carcinoma cell line, WiDr; in addition, there was a two- to three-fold increase in the expression of a tumor-associated antigen, carcinoembryonic antigen. In contrast, interferon had no effect on a normal human diploid cell line, WI-38. Thus, in addition to its anti-cellular effect against tumor cells, interferon can also modulate tumor antigenicity.

摘要

相似文献

1
Enhancement of carcinoembryonic antigen expression by interferon.
Int J Cancer. 1979 Jul 15;24(1):49-52. doi: 10.1002/ijc.2910240109.
2
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