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植入大鼠皮下腔室的流体和药理动力学

Fluid and pharmacological dynamics in a subcutaneous chamber implanted in rats.

作者信息

Gardner W G, Prior R B, Perkins R L

出版信息

Antimicrob Agents Chemother. 1973 Aug;4(2):196-7. doi: 10.1128/AAC.4.2.196.

DOI:10.1128/AAC.4.2.196
PMID:4790940
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC444527/
Abstract

Antibiotic dynamics in the fluid obtained from subcutaneously implanted chambers in rats were similar to those observed in serum following single intramuscular injections of carbenicillin.

摘要

从大鼠皮下植入腔室获得的液体中的抗生素动力学与单次肌内注射羧苄青霉素后血清中观察到的动力学相似。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7b7/444527/c1202aa1ced1/aac00350-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7b7/444527/c1202aa1ced1/aac00350-0124-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a7b7/444527/c1202aa1ced1/aac00350-0124-a.jpg

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本文引用的文献

1
Neisseria gonorrhoeae: experimental infection of laboratory animals.淋病奈瑟菌：实验动物的感染实验
Science. 1972 Sep 29;177(4055):1200-1. doi: 10.1126/science.177.4055.1200.
2
Implantation and use of a subcutaneous culture chamber in laboratory animals.皮下培养室在实验动物中的植入与应用。
Lab Anim Sci. 1973 Feb;23(1):105-6.
植入兔软组织和肾脏的扩散室中液体的成分。
Infection. 1980;8(4):156-61. doi: 10.1007/BF01639123.
4
The granuloma pouch: an in vivo model for pharmacokinetic and chemotherapeutic investigations. I. Biochemical and histological characterization.肉芽肿袋：一种用于药代动力学和化疗研究的体内模型。I. 生化和组织学特征
Infection. 1982 Nov-Dec;10(6):354-60. doi: 10.1007/BF01642299.
5
Evaluation of a tissue cage model for use in cattle.用于牛的组织笼模型评估。
Acta Vet Scand. 1984;25(4):480-94. doi: 10.1186/BF03546916.
6
Morphological alterations of Pseudomonas aeruginosa by ticarcillin: a scanning electron microscope study.替卡西林对铜绿假单胞菌的形态学改变：一项扫描电子显微镜研究。
Antimicrob Agents Chemother. 1974 Dec;6(6):853-5. doi: 10.1128/AAC.6.6.853.
7
Bacampicillin: a new orally well-absorbed derivative of ampicillin.巴卡西林：一种新的口服吸收良好的氨苄西林衍生物。
Antimicrob Agents Chemother. 1975 Nov;8(5):518-25. doi: 10.1128/AAC.8.5.518.
8
Fluid and penicillin G dynamics in polyethylene chambers implanted subcutaneously in rabbits.兔皮下植入聚乙烯腔室中的液体及青霉素G动力学
Antimicrob Agents Chemother. 1975 Oct;8(4):495-7. doi: 10.1128/AAC.8.4.495.
9
Penetration of cefamandole, cephalothin, and desacetylcephalothin into fibrin clots.头孢孟多、头孢噻吩和去乙酰头孢噻吩在纤维蛋白凝块中的渗透。
Antimicrob Agents Chemother. 1977 Dec;12(6):682-7. doi: 10.1128/AAC.12.6.682.
10
Treponema pallidum infection in subcutaneous polyethylene chambers in rabbits.兔皮下聚乙烯腔室中的梅毒螺旋体感染
Infect Immun. 1976 Jun;13(6):1606-12. doi: 10.1128/iai.13.6.1606-1612.1976.