Hasselbacher P
J Lab Clin Med. 1979 Oct;94(4):532-41.
IgG adsorbed to negatively charged crystals of monosodium urate monohydrate was restricted to cationic species of immunoglobulin. Similar binding of smaller amounts of IgG was observed with crystals other than monosodium urate monohydrate. Heated monosodium urate monohydrate and amorphous sodium urate adsorbed greater amounts of IgG and other proteins. Complement activation as measured by electrophoretic conversion of C3, was not related to the amount of IgG adsorbed by the crystals studied. C1q was also adsorbed to some degree by all crystals studied but did not correlate with complement activation.
吸附于一水合尿酸钠带负电荷晶体上的IgG仅限于免疫球蛋白的阳离子种类。在除一水合尿酸钠之外的晶体中也观察到了较少量IgG的类似结合。加热的一水合尿酸钠和无定形尿酸钠吸附了更多的IgG和其他蛋白质。通过C3的电泳转化测定的补体激活与所研究晶体吸附的IgG量无关。所研究的所有晶体也都在一定程度上吸附了C1q，但与补体激活无关。
