Miller D S, Parsonage S
Lancet. 1975 Apr 5;1(7910):773-5. doi: 10.1016/s0140-6736(75)92437-x.
Twenty-nine women who claimed that they could not lose weight on prescribed diets were isolated in a country house and fed 1500 kcal. per day for 3 weeks. Nine women maintained weight within plus or minus 1 kg. and were characterised by low basal (B.M.R.) and daily metabolic rates and by a long previous history of dieting. The remaining women did lose weight, but there was much individual variation. B.M.R. is a good indicator of probable weight loss as a result of dieting. In the group as a whole it was more closely related to body fat than to lean body mass. It was also related to fat-cell number as determined by biopsy, but not to fat-cell size. These findings suggest that among a group of would-be slimmers who claim to be unable to lose weight there will be some who have become metabolically adapted to a low-energy diet and others whose inability to lose weight is illusory.
29名声称按照规定饮食无法减肥的女性被隔离在一所乡间别墅里，每天摄入1500千卡热量，持续3周。9名女性体重维持在±1千克以内，其特点是基础代谢率（B.M.R.）和每日代谢率较低，且有长期节食史。其余女性确实减轻了体重，但个体差异很大。基础代谢率是节食可能导致体重减轻的一个良好指标。在整个组中，它与体脂的关系比与瘦体重的关系更密切。它也与通过活检确定的脂肪细胞数量有关，但与脂肪细胞大小无关。这些发现表明，在一群自称无法减肥的潜在减肥者中，会有一些人已经在代谢上适应了低能量饮食，而另一些人无法减肥则是假象。
