乳腺癌患者对肿瘤细胞和胚胎细胞的免疫反应。
Immune responses to tumour and embryo cells in patients with mammary carcinoma.
作者信息
Della Porta G, Canevari S, Fossati G
出版信息
Br J Cancer Suppl. 1973 Aug;1:103-7.
Abstract
Cytotoxicity microassays were used to study cellular and humoral responses of patients with breast carcinoma against in vitro cultured target cells of breast carcinomata and of human embryos. Peripheral lymphocytes were cytotoxic on both target cell types, whereas sera exerted a complement-dependent cytotoxicity on breast cancer cells only. The immunosensitivity of the breast cancer cells to patient lymphocytes was augmented by restraining cell growth before test with a decreased quantity of foetal calf serum.
摘要
细胞毒性微量分析用于研究乳腺癌患者对体外培养的乳腺癌细胞和人类胚胎靶细胞的细胞和体液反应。外周淋巴细胞对两种靶细胞类型均具有细胞毒性，而血清仅对乳腺癌细胞发挥补体依赖性细胞毒性。在用减少量的胎牛血清进行测试前，通过抑制细胞生长可增强乳腺癌细胞对患者淋巴细胞的免疫敏感性。
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Immune responses to tumour and embryo cells in patients with mammary carcinoma.乳腺癌患者对肿瘤细胞和胚胎细胞的免疫反应。
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引用本文的文献
1
Isolation from patients with breast cancer of antibodies specific for antigens associated with breast cancer and other malignant diseases.从乳腺癌患者中分离出对与乳腺癌及其他恶性疾病相关抗原具有特异性的抗体。
Proc Natl Acad Sci U S A. 1976 Jun;73(6):2101-5. doi: 10.1073/pnas.73.6.2101.
2
Cell-mediated anti-embryo cytotoxicity in human pregnancy.人类妊娠中细胞介导的抗胚胎细胞毒性
Clin Exp Immunol. 1976 Mar;23(3):462-70.
3
[The lymphocyte cytotoxicity test in tumor immunology (author's transl)].肿瘤免疫学中的淋巴细胞细胞毒性试验（作者译）
Klin Wochenschr. 1975 Jan;53(1):1-6. doi: 10.1007/BF01466850.
本文引用的文献
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Effect of autologous mammary tumour extracts on human leukocyte migration in vitro.自体乳腺肿瘤提取物对人白细胞体外迁移的影响。
Int J Cancer. 1970 May 15;5(3):357-63. doi: 10.1002/ijc.2910050308.
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Humoral cross immunity in patients with malignant tumors.恶性肿瘤患者的体液交叉免疫
Arch Immunol Ther Exp (Warsz). 1971;19(6):835-49.
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Cellular and humoral immunity against human malignant melanoma.针对人类恶性黑色素瘤的细胞免疫和体液免疫。
Int J Cancer. 1971 Sep 15;8(2):344-50. doi: 10.1002/ijc.2910080221.
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Neutralization of murine mammary tumour virus by sera of women with breast cancer.乳腺癌患者血清对小鼠乳腺肿瘤病毒的中和作用。
Nature. 1971 Feb 26;229(5287):627-8. doi: 10.1038/229627a0.
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Evidence for virus-related and unrelated antigens on murine lymphomas induced by chemical carcinogens.化学致癌物诱导的小鼠淋巴瘤上与病毒相关和不相关抗原的证据。
J Natl Cancer Inst. 1973 Jan;50(1):173-80. doi: 10.1093/jnci/50.1.173.
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Cellular immunity to human breast carcinoma.
Int J Cancer. 1972 Sep 15;10(2):391-6. doi: 10.1002/ijc.2910100221.
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[Specific immunogenicity of human mammary carcinoma extracts in rabbits].[人乳腺癌提取物在兔体内的特异性免疫原性]
Tumori. 1972 May-Jun;58(3):157-63. doi: 10.1177/030089167205800304.
9
Fluorescent antibody studies of human breast cancer.人类乳腺癌的荧光抗体研究。
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Embryonic antigen expression in chemically induced rat hepatomas and sarcomas.化学诱导的大鼠肝癌和肉瘤中胚胎抗原的表达
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