Della Porta G, Canevari S, Fossati G
Br J Cancer Suppl. 1973 Aug;1:103-7.
Cytotoxicity microassays were used to study cellular and humoral responses of patients with breast carcinoma against in vitro cultured target cells of breast carcinomata and of human embryos. Peripheral lymphocytes were cytotoxic on both target cell types, whereas sera exerted a complement-dependent cytotoxicity on breast cancer cells only. The immunosensitivity of the breast cancer cells to patient lymphocytes was augmented by restraining cell growth before test with a decreased quantity of foetal calf serum.
细胞毒性微量分析用于研究乳腺癌患者对体外培养的乳腺癌细胞和人类胚胎靶细胞的细胞和体液反应。外周淋巴细胞对两种靶细胞类型均具有细胞毒性，而血清仅对乳腺癌细胞发挥补体依赖性细胞毒性。在用减少量的胎牛血清进行测试前，通过抑制细胞生长可增强乳腺癌细胞对患者淋巴细胞的免疫敏感性。
