Kolev K, Dimitrov T
Eksp Med Morfol. 1973;12(2):81-6.
Results are submitted of studies on the influence exerted by cement dust, introduced into the peritoneal cavity and lung of experimental animals. The difference recorded are explained by the low free silicon dioxide content in the cement investigated and to the presence of additional chemical ingredients. The inference is reached that in the course of testing dusts with high free silicon dioxide content and determinations of the fibrinogenous action of the dust investigated, the two methods yield approximately identical results. Anyway, during studies of dusts with low silica content in the presence of additional chemical components, and determinations of their general toxic and biological action, the results obtained by either of the methods should be distinguished and separately evaluated. The organs of the pleural cavity, respectivly the lung, are more feasible for investigation of the fibrinogenic activity of dusts, whilst the peritoneal cavity is more suitable for investigation of the cumulative action of dusts with fibrous and toxic effect.
本文呈现了关于将水泥粉尘引入实验动物腹腔和肺部所产生影响的研究结果。所记录的差异可归因于所研究水泥中游离二氧化硅含量较低以及存在其他化学成分。由此推断,在测试高游离二氧化硅含量粉尘并测定所研究粉尘的纤维蛋白原生成作用时,这两种方法产生的结果大致相同。无论如何,在研究存在其他化学成分的低硅含量粉尘并测定其一般毒性和生物作用时,两种方法所获得的结果应加以区分并分别评估。胸腔器官,即肺部,更适合用于研究粉尘的纤维蛋白原生成活性,而腹腔则更适合用于研究具有纤维性和毒性作用粉尘的累积作用。