Rieger G
Klin Monbl Augenheilkd. 1979 Mar;174(3):360-5.
The author points out in connection with the description of two families in which evidently several children suffered damage through toxoplasmosis with which the mother had been infected a long time ago (pseudocoloboma of the macula, changes of the macula similar to juvenile degreneration, abortion and malformations such as anophthalmia, rhinoschisis, cheiloschisis, gnathoschisis and palatoschisis), that low titer levels in the Sabin-Feldmann test and in the complement fixation test are by no means totally insignificant for subsequent pregnancies, as is commonly assumed. In any case, women who have already given birth to children with congenital toxoplasmosis should be subjected to toxoplasmosis treatment, as far as possible, before any new pregnancy.
作者在描述两个家庭时指出,其中显然有几个孩子因母亲多年前感染的弓形虫病而受损(黄斑部假性缺损、类似于青少年变性的黄斑变化、流产以及诸如无眼、鼻裂、唇裂、颌裂和腭裂等畸形),认为萨宾 - 费尔德曼试验和补体结合试验中的低滴度水平,绝非像通常所认为的那样对后续妊娠完全无足轻重。无论如何,已经生育过先天性弓形虫病患儿的妇女,在任何新的妊娠之前,应尽可能接受弓形虫病治疗。