初步通讯
Preliminary communications.
作者信息
Stanciu C, Bennett J R
出版信息
Br Med J. 1974 Feb 23;1(5903):312-3. doi: 10.1136/bmj.1.5903.312.
Abstract
The effects of pentazocine on colonic motor activity were studied in five normal subjects, five patients with irritable bowel syndrome, and five patients with diverticular disease. The drug decreased intraluminal colonic pressures in all patients but one. Since morphine, which increases intraluminal colonic pressures, is contraindicated in patients with abdominal pain of colonic origin (diverticular disease, irritable bowel syndrome), we suggest that pentazocine may be a useful drug in such cases.
摘要
在五名正常受试者、五名肠易激综合征患者和五名憩室病患者中研究了喷他佐辛对结肠运动活性的影响。除一名患者外，该药物降低了所有患者的结肠腔内压力。由于吗啡会增加结肠腔内压力，在患有结肠源性腹痛（憩室病、肠易激综合征）的患者中禁用，因此我们建议喷他佐辛在这类病例中可能是一种有用的药物。
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