Korobkin R, Guilleminault C
Pediatrics. 1979 Sep;64(3):369-74.
As part of the Sudden Death Research Project at Stanford University School of Medicine, we have performed systematic neurologic examination of 41 near miss infants, 7 normal siblings of babies who died a sudden infant death, and 21 normal control infants. Many infants were examined longitudinally until 2 years of age. We found that near miss infants under 3 months of age had consistent abnormalities of muscle tone, particularly shoulder hypotonia. These abnormalities disappeared with maturation, but only 60% of older infants who had suffered near miss episodes of neurologically and developmentally normal. In addition, only one of the seven apparently normal siblings had an entirely normal neurologic examination when first seen. Thus, infants who present with near miss episodes may have an underlying central nervous system abnormality or may acquire some abnormality as a result of the episode.
作为斯坦福大学医学院猝死研究项目的一部分，我们对41名濒死婴儿、7名死于婴儿猝死综合征的婴儿的正常兄弟姐妹以及21名正常对照婴儿进行了系统的神经系统检查。许多婴儿接受了纵向检查，直至2岁。我们发现，3个月以下的濒死婴儿存在持续的肌张力异常，尤其是肩部肌张力减退。这些异常随着成熟而消失，但在神经和发育正常的濒死发作的大龄婴儿中，只有60%恢复正常。此外，在首次检查时，7名明显正常的兄弟姐妹中只有1人神经系统检查完全正常。因此，出现濒死发作的婴儿可能存在潜在的中枢神经系统异常，或者可能由于发作而出现一些异常。
