Kahn A, Riazi J, Blum D
Pediatrics. 1983 Jan;71(1):49-52.
To gain insight into the role of the vagus nerve in sudden infant death syndrome (SIDS), 180 infants ranging in age from 1 to 66 weeks were examined with respect to cardiac response to ocular compression. There were 35 near-miss infants, 76 normal siblings of SIDS victims, and 69 normal control infants. Asystoles within the control group ranged from 0.3 to 1.8 seconds. Ten of 35 (28%) near-miss infants and 10/76 (13%) siblings had asystoles greater than 2.0 seconds when first tested. When statistically compared, the near-miss infants were significantly different from both the control infants and the siblings (Kruskal-Wallis procedure: P less than .01, and P less than .05, respectively). It is concluded that in the first year of life a significant number of near-miss infants have an exaggerated cardiac response to ocular compression. Furthermore, the presence of prolonged asystoles in certain siblings indicates that vagal hypersensitivity, as manifested by ocular compression, may be, in part, hereditary.
为深入了解迷走神经在婴儿猝死综合征（SIDS）中的作用，对180名年龄在1至66周的婴儿进行了眼部压迫心脏反应检查。其中有35名濒死婴儿、76名SIDS受害者的正常兄弟姐妹以及69名正常对照婴儿。对照组的心脏停搏时间为0.3至1.8秒。首次测试时，35名濒死婴儿中有10名（28%）以及76名兄弟姐妹中有10名（13%）的心脏停搏时间超过2.0秒。经统计学比较，濒死婴儿与对照婴儿和兄弟姐妹均存在显著差异（Kruskal-Wallis检验：P值分别小于0.01和0.05）。研究得出结论，在生命的第一年，相当数量的濒死婴儿对眼部压迫有过度的心脏反应。此外，某些兄弟姐妹中出现的长时间心脏停搏表明，眼部压迫所表现出的迷走神经超敏反应可能部分具有遗传性。
