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家具行业木工的鼻黏膜纤毛清除功能受损。

Impairment of nasal mucociliary clearance in woodworkers in the furniture industry.

作者信息

Black A, Evans J C, Hadfield E H, Macbeth R G, Morgan A, Walsh M

出版信息

Br J Ind Med. 1974 Jan;31(1):10-7. doi: 10.1136/oem.31.1.10.

Abstract

10-17. Measurements of mucociliary clearance from the anterior end of the middle turbinate were made using technetium-99m-labelled particles in nine woodworkers from the furniture industry and in 12 controls, none of whom had been occupationally exposed to wood dust. Clearance rates in the controls ranged from 1·9 to 18·5 mm min with a mean of 6·8. These values are in good agreement with measurements reported elsewhere for normal subjects. Only one of the woodworkers had a clearance rate which fell within the normal range and he had been occupationally exposed for the shortest period (6 years). In four woodworkers clearance was very slow (< 1 mm min) and in three there was almost complete stasis. The results of this preliminary investigation suggest that nasal mucociliary function is significantly impaired in workers who have been exposed to wood dust in the furniture industry for more than 10 years.

摘要

10 - 17. 利用锝 - 99m标记的颗粒,对9名来自家具行业的木工以及12名对照者的中鼻甲前端的黏液纤毛清除功能进行了测量,这些对照者均未职业性接触过木屑。对照者的清除率范围为1.9至18.5毫米/分钟,平均为6.8。这些数值与其他地方报道的正常受试者的测量结果高度一致。只有一名木工的清除率在正常范围内,且他的职业接触时间最短(6年)。在四名木工中,清除非常缓慢(<1毫米/分钟),在三名木工中几乎完全停滞。这项初步调查的结果表明,在家具行业中接触木屑超过10年的工人,其鼻黏液纤毛功能会受到显著损害。

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本文引用的文献

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CLEARANCE OF PARTICLES FROM THE HUMAN NOSE. PRELIMINARY REPORT.
Arch Environ Health. 1965 Sep;11:366-71. doi: 10.1080/00039896.1965.10664231.
2
Measurement of mucociliary function in man.
Am Rev Respir Dis. 1969 Jan;99(1):13-23. doi: 10.1164/arrd.1969.99.1.13.
3
Nasal cancer in woodworkers in the furniture industry.家具行业木工中的鼻癌
Br Med J. 1968 Jun 8;2(5605):587-96. doi: 10.1136/bmj.2.5605.587.
5
Human nasal mucosal function in a controlled climate.可控气候条件下的人体鼻黏膜功能
Arch Environ Health. 1971 Dec;23(6):408-20. doi: 10.1080/00039896.1971.10666029.
6
Adenocarcinoma of ethmoids in furniture workers.家具工人筛窦腺癌
Ann Otol Rhinol Laryngol. 1971 Oct;80(5):699-703. doi: 10.1177/000348947108000512.
9
Carcinoma of the nasal cavity and accessory sinuses in woodworkers.木工鼻腔及鼻窦癌
Lancet. 1967 Feb 11;1(7485):311-2. doi: 10.1016/s0140-6736(67)91243-3.

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