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支原体病毒MVL51的细胞内复制

Intracellular replication of mycoplasmavirus MVL51.

作者信息

Liss A, Maniloff J

出版信息

J Virol. 1974 Apr;13(4):769-74. doi: 10.1128/JVI.13.4.769-774.1974.

DOI:10.1128/JVI.13.4.769-774.1974
PMID:4821487
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC355374/
Abstract

The intracellular replication of MVL51, a group L1 mycoplasmavirus, was investigated. The single-stranded parental DNA was found to enter the cell and become converted to double-stranded DNA. This replicated to yield additional double-stranded DNA molecules. The parental viral DNA was found to leave the replication complex and become associated with large molecular weight DNA not involved with viral replication. Progeny viral DNA formed from the double-stranded DNA and an intracellular accumulation of virus chromosome size DNA was observed. The interpretation of this data and a suggested model for the viral replication are discussed and compared to viral DNA replication models for other single-stranded DNA viruses.

摘要

对L1组支原体病毒MVL51的细胞内复制进行了研究。发现单链亲代DNA进入细胞并转化为双链DNA。该双链DNA进行复制以产生更多双链DNA分子。发现亲代病毒DNA离开复制复合体并与不参与病毒复制的大分子DNA结合。观察到由双链DNA形成的子代病毒DNA以及病毒染色体大小DNA的细胞内积累。讨论了这些数据的解释以及病毒复制的建议模型，并与其他单链DNA病毒的病毒DNA复制模型进行了比较。

相似文献

1
Intracellular replication of mycoplasmavirus MVL51.支原体病毒MVL51的细胞内复制
J Virol. 1974 Apr;13(4):769-74. doi: 10.1128/JVI.13.4.769-774.1974.
2
Replication of mycoplasmavirus MVL51: attachment of MVL51 parental DNA to host cell membrane.支原体病毒MVL51的复制：MVL51亲代DNA与宿主细胞膜的附着。
Proc Natl Acad Sci U S A. 1976 May;73(5):1489-93. doi: 10.1073/pnas.73.5.1489.
3
Replication of mycoplasmavirus MVL51. IV. Inhibition of viral synthesis by rifampin.支原体病毒MVL51的复制。IV. 利福平对病毒合成的抑制作用。
J Virol. 1976 Jun;18(3):969-76. doi: 10.1128/JVI.18.3.969-976.1976.
4
Replication of mycoplasmavirus MVL51. III. Identification of a progeny viral DNA-protein intermediate.
Microbios. 1976;15(60):127-34.
5
Replication of mycoplasmavirus MVL51: I. Replicative intermediates.
Biochem Biophys Res Commun. 1975 Sep 16;66(2):599-605. doi: 10.1016/0006-291x(75)90552-5.
6
Replication of mycoplasmavirus MVL51: VI. Acriflavine stimulates growth of this single-stranded DNA virus.
Biochem Biophys Res Commun. 1979 Jul 27;89(2):643-9. doi: 10.1016/0006-291x(79)90678-8.
7
Replication of mycoplasmavirus MVL51. V. In vivo synthesis of virus-specific proteins.
Virology. 1978 May 1;86(1):186-92. doi: 10.1016/0042-6822(78)90019-3.
8
Characterization of an Acholeplasma laidlawii variant with a REP- phenotype.一株具有REP-表型的莱氏无胆甾原体变体的特性分析。
J Bacteriol. 1976 Aug;127(2):832-6. doi: 10.1128/jb.127.2.832-836.1976.
9
Virus and host cell DNA syntheses during infection of Acholeplasma laidlawii by MVL3, a nonlytic cytocidal mycoplasmavirus.MVL3（一种非裂解性杀细胞支原体病毒）感染莱氏无胆甾原体期间的病毒和宿主细胞DNA合成
J Virol. 1980 Feb;33(2):671-9. doi: 10.1128/JVI.33.2.671-679.1980.
10
Structural and biological properties of mycoplasmavirus MVL3: an unusual virus-procaryote interaction.支原体病毒MVL3的结构与生物学特性：一种不同寻常的病毒-原核生物相互作用
J Virol. 1979 Oct;32(1):268-75. doi: 10.1128/JVI.32.1.268-275.1979.

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