一株具有REP-表型的莱氏无胆甾原体变体的特性分析。
Characterization of an Acholeplasma laidlawii variant with a REP- phenotype.
作者信息
Nowak J A, Das J, Maniloff J
出版信息
J Bacteriol. 1976 Aug;127(2):832-6. doi: 10.1128/jb.127.2.832-836.1976.
Abstract
An Acholeplasma laidlawii variant has been isolated that has a REP- phenotype. The properties of this variant, relative to parental cells, are: (i) it exhibits no change in cell growth kinetics; (ii) it does not propagate single-stranded deoxyribonucleic acid (DNA) mycoplasmaviruses but does propagate double-stranded DNA mycoplasmaviruses; (iii) it converts parental circular single-stranded mycoplasmavirus DNA to double-stranded replicative forms that are not replicated further; (iv) it exhibits no change in host modification and restriction; and (v) it has an increased ultraviolet light sensitivity. The REP- isolate is the first stable mycoplasma variant to which a physiological defect has been attributed.
摘要
已分离出一种具有REP-表型的莱氏无胆甾原体变种。相对于亲代细胞，该变种的特性如下：（i）其细胞生长动力学无变化；（ii）它不能传播单链脱氧核糖核酸（DNA）支原体病毒，但能传播双链DNA支原体病毒；（iii）它将亲代环状单链支原体病毒DNA转化为双链复制形式，但这些复制形式不再进一步复制；（iv）其宿主修饰和限制无变化；（v）它对紫外线的敏感性增加。该REP-分离株是首个被归因于生理缺陷的稳定支原体变种。
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