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支原体病毒MVL3的结构与生物学特性:一种不同寻常的病毒-原核生物相互作用

Structural and biological properties of mycoplasmavirus MVL3: an unusual virus-procaryote interaction.

作者信息

Haberer K, Klotz G, Maniloff J, Kleinschmidt A K

出版信息

J Virol. 1979 Oct;32(1):268-75. doi: 10.1128/JVI.32.1.268-275.1979.

DOI:10.1128/JVI.32.1.268-275.1979
PMID:541825
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC353551/
Abstract

The kinetics of adsorption and growth of mycoplasmavirus MVL3 in Acholeplasma laidlawii 1305/68 host cells have been studied with one-step growth, premature lysis, and single-burst experiments. The virus was found to kill infected host cells. Virus release starts 90 min after infection and continues for about 10 to 15 h. Hence, virus production is unlike the classical lytic bacteriophages and instead resembles nonlytic cytocidal animal viruses. Structural details of the virus are described, and the molecular weight of the viral linear DNA has beenfound to be 26 x 10(6).

摘要

通过一步生长、过早裂解和单步增殖实验,研究了支原体病毒MVL3在莱氏无胆甾原体1305/68宿主细胞中的吸附和生长动力学。发现该病毒会杀死受感染的宿主细胞。病毒释放于感染后90分钟开始,并持续约10至15小时。因此,病毒产生不同于经典的裂解性噬菌体,而是类似于非裂解性杀细胞动物病毒。描述了该病毒的结构细节,并且发现病毒线性DNA的分子量为26×10⁶ 。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38d4/353551/dd0809afcea2/jvirol00190-0281-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38d4/353551/bf3b7c6cac9e/jvirol00190-0280-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38d4/353551/dd0809afcea2/jvirol00190-0281-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38d4/353551/bf3b7c6cac9e/jvirol00190-0280-a.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/38d4/353551/dd0809afcea2/jvirol00190-0281-a.jpg

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Structural and biological properties of mycoplasmavirus MVL3: an unusual virus-procaryote interaction.支原体病毒MVL3的结构与生物学特性:一种不同寻常的病毒-原核生物相互作用
J Virol. 1979 Oct;32(1):268-75. doi: 10.1128/JVI.32.1.268-275.1979.
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引用本文的文献

1
Adsorption, capping, and release of a complex bacteriophage by mycoplasma cells.
J Virol. 1980 Oct;36(1):264-70. doi: 10.1128/JVI.36.1.264-270.1980.
2
Virus and host cell DNA syntheses during infection of Acholeplasma laidlawii by MVL3, a nonlytic cytocidal mycoplasmavirus.MVL3(一种非裂解性杀细胞支原体病毒)感染莱氏无胆甾原体期间的病毒和宿主细胞DNA合成
J Virol. 1980 Feb;33(2):671-9. doi: 10.1128/JVI.33.2.671-679.1980.
3
Lateral mobility of membrane-bound antibodies on the surface of Acholeplasma laidlawii: evidence for virus-induced cell fusion in a procaryote.莱氏无胆甾原体表面膜结合抗体的侧向移动性:原核生物中病毒诱导细胞融合的证据。

本文引用的文献

1
The intracellular growth of bacteriophages. I. Liberation of intracellular bacteriophage T4 by premature lysis with another phage or with cyanide.噬菌体的细胞内生长。I. 用另一种噬菌体或氰化物进行过早裂解以释放细胞内噬菌体T4
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Isolation of mycoplasma virus L2 insertion variants and miniviruses.支原体病毒L2插入变体和微小病毒的分离
J Virol. 1986 Sep;59(3):584-90. doi: 10.1128/JVI.59.3.584-590.1986.
8
Mapping of mycoplasma virus DNA replication origins and termini.支原体病毒DNA复制起始点和终点的定位
J Virol. 1987 Jun;61(6):1909-12. doi: 10.1128/JVI.61.6.1909-1912.1987.
9
Electroporation-mediated transfection of Acholeplasma laidlawii with mycoplasma virus L1 and L3 DNA.用电穿孔法将支原体病毒L1和L3 DNA转染莱氏无胆甾原体。
J Virol. 1988 Aug;62(8):3050-2. doi: 10.1128/JVI.62.8.3050-3052.1988.
10
Mycoplasma restriction: identification of a new type of restriction specificity for DNA containing 5-methylcytosine.支原体限制作用:对含5-甲基胞嘧啶DNA的新型限制特异性的鉴定
J Bacteriol. 1986 Jan;165(1):219-25. doi: 10.1128/jb.165.1.219-225.1986.
Biophys J. 1971 Jul;11(7):572-81. doi: 10.1016/S0006-3495(71)86236-7.
4
Isolation of mycoplasmatales virus-laidlawii 3, a new virus infecting Acholeplasma laidlawii.支原体病毒-莱氏无胆甾原体3的分离,一种感染莱氏无胆甾原体的新病毒。
J Gen Virol. 1973 May;19(2):279-83. doi: 10.1099/0022-1317-19-2-279.
5
Eagle's basal medium as a defined medium for Mycoplasma studies.伊格尔基础培养基作为支原体研究的限定培养基。
Microbios. 1972 Sep-Oct;6(22):179-85.
6
Mycoplasmatales virus-laidlawii 2, a new virus isolated from Acholeplasma laidlawii.支原体病毒-莱氏无胆甾原体2,一种从莱氏无胆甾原体中分离出的新病毒。
J Gen Virol. 1971 Jul;12(1):65-7. doi: 10.1099/0022-1317-12-1-65.
7
Characterization of Mycoplasmatales virus-laidlawii 3.
J Gen Virol. 1975 Oct;29(1):11-24. doi: 10.1099/0022-1317-29-1-11.
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Acholeplasma laidlawii infection by group 3 mycoplasmavirus.
Virology. 1977 Mar;77(1):433-6. doi: 10.1016/0042-6822(77)90443-3.
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Characterization of mycoplasmavirus MVL2 DNA.支原体病毒MVL2 DNA的特性分析
J Virol. 1979 Jan;29(1):381-4. doi: 10.1128/JVI.29.1.381-384.1979.
10
Physical characterization of the superhelical DNA genome of an enveloped mycoplasmavirus.一种包膜支原体病毒超螺旋DNA基因组的物理特性分析
J Virol. 1979 Jan;29(1):374-80. doi: 10.1128/JVI.29.1.374-380.1979.