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年轻哮喘患者运动期间的肺气体交换

Pulmonary gas exchange during exercise in young asthmatic patients.

作者信息

Feisal K A, Fuleihan F J

出版信息

Thorax. 1979 Jun;34(3):393-6. doi: 10.1136/thx.34.3.393.

Abstract

Pulmonary function was examined in 19 young asthmatic patients at rest and during two levels of excercise. Findings at rest included decreased flow rates, increased residual volume, normal minute (VE) and alveolar (VA) ventilation, increased ratio of physiological dead space to tidal volume (VD/VT), increased alveolar-arterial oxygen tension difference (A-a PO2), and mild arterial hypoxaemia and desaturation. On exercise there was a normal increase in VE and VA, the VD/VT and the A-a PO2 decreased towards normal, and arterial oxygen tension improved, approaching normal levels. Significant acidosis did not develop.

摘要

对19名年轻哮喘患者在静息状态和两个运动水平下进行了肺功能检查。静息状态下的检查结果包括流速降低、残气量增加、分钟通气量(VE)和肺泡通气量(VA)正常、生理死腔与潮气量之比(VD/VT)增加、肺泡-动脉氧分压差(A-a PO2)增加,以及轻度动脉低氧血症和氧饱和度降低。运动时,VE和VA正常增加,VD/VT和A-a PO2向正常水平降低,动脉氧分压改善,接近正常水平。未出现明显酸中毒。

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本文引用的文献

2
CONTROLLED EXERCISE IN ASTHMATIC CHILDREN.
Ann Allergy. 1965 May;23:220-5.
4
Distribution of gas and blood in the normal lungs.正常肺内气体与血液的分布
Br Med Bull. 1963 Jan;19:53-8. doi: 10.1093/oxfordjournals.bmb.a070007.
7
Respiratory gas exchange at rest and during exercise in normal and asthmatic children.
Am Rev Respir Dis. 1967 Feb;95(2):248-54. doi: 10.1164/arrd.1967.95.2.248.
10
Alveolar-arterial gas tension differences during graded exercise.
J Appl Physiol. 1969 Sep;27(3):361-5. doi: 10.1152/jappl.1969.27.3.361.

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