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[在互补试验中研究的委内瑞拉马脑炎病毒温度敏感突变体]

[Temperature-sensitive mutants of the Venezuelan equine encephalomyelitis virus studied in the complementation test].

作者信息

Vlasyko G V, Tsilinskii Ia Ia

出版信息

Vopr Virusol. 1979 Jul-Aug(4):406-9.

PMID:483775
Abstract

Investigation of 15 ts mutants of Venezuelan equine encephalomyelitis (VEE) virus by complementation tests permitted to divide these mutants into 5 complementation groups and to distinguish unclassifiable mutants. Mutants of 2 groups had RNA+/- or RNA- phenotype, i. e. had defects in RNA synthesis. Mutants in the other 3 groups had the RNA+ phenotype, and the temperature-sensitive defect of these mutants was in later stages of virus reproduction.

摘要

通过互补试验对委内瑞拉马脑炎(VEE)病毒的15个ts突变体进行研究,可将这些突变体分为5个互补组,并区分出无法分类的突变体。2个组的突变体具有RNA+/-或RNA-表型,即RNA合成存在缺陷。其他3个组的突变体具有RNA+表型,这些突变体的温度敏感性缺陷出现在病毒繁殖的后期阶段。

相似文献

1
[Temperature-sensitive mutants of the Venezuelan equine encephalomyelitis virus studied in the complementation test].[在互补试验中研究的委内瑞拉马脑炎病毒温度敏感突变体]
Vopr Virusol. 1979 Jul-Aug(4):406-9.
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