Daikoku N H, Tyson J E, Graf C, Scott R, Smith B, Johnson J W, King T M
Am J Obstet Gynecol. 1979 Oct 15;135(4):516-21. doi: 10.1016/0002-9378(79)90443-5.
The purpose of this prospective study was to determine whether serial maternal venous hPL determinations could identify pregnancies resulting in growth-retarded infants from a selected population at presumed high risk for IUGR. Our results demonstrated that mean hPL levels in IUGR outcome pregnancies were significantly lower than normal after 33 weeks' gestation. Mean hPL was also lower in some pregnancies resulting in normal-weight neonates with abnormally low PI or short CHL, suggesting that these neonates, despite normal birth weight achievement, may represent previously unsuspected.
这项前瞻性研究的目的是确定连续测定孕妇静脉血中胎盘催乳素（hPL）是否能够从一组被认为患胎儿生长受限（IUGR）风险较高的特定人群中识别出会导致胎儿生长迟缓的妊娠。我们的结果表明，在妊娠33周后，IUGR结局妊娠的hPL平均水平显著低于正常水平。在一些产出体重正常但搏动指数（PI）异常低或头臀长度（CHL）短的新生儿的妊娠中，hPL平均水平也较低，这表明这些新生儿尽管出生体重正常，但可能代表着之前未被怀疑的情况。
