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[胃肠疾病的肛门症状]

[Anal symptoms of gastro-intestinal diseases].

作者信息

Grosshans E, Jenn P, Baumann R, Weill J P, Basset A

出版信息

Ann Dermatol Venereol. 1979 Jan;106(1):25-30.

PMID:485013
Abstract

In most cases the ano-cutaneous clinical symptoms correlated to diseases of the gastro-intestinal tract are not specific (erythema, itching, wounds or scarring). However in the following diseases occasional dermatological lesions may directly contribute to their diagnosis: in Crohn's disease, tuberculosis of bowel, chronic entamoebiasis and bilharziosis, the skin lesions of the anal area have the same histological structure as the gut lesions. Perianal fistulas and ulcers are frequent in Crohn's disease especially if there is a colonic and rectal spreading; they respond badly to steroid therapy and are often correlated with a worse prognosis. Perianal specific lesions occur often in oxyuriasis in children, in candidiasis of the digestive tract, in systemic aphthosis and in some malignancies. In other gastro-intestinal disturbances, the dermatological and features are less specific and can only be suggestive: iatrogenic and microbial diarrheas, side-effects of laxatives, proctological diseases. It has to be emphasized that pruritus ani is only induced by deeper lesions when they spread to the perianal skin. In proctological practice, contact dermatitis by sensitivity to anaesthetics or suppository balsams (Peruvian balsam), itching or burning atrophy by topical steroid abuse, non-diagnosed fungal (candidiasis), bacterial (erythrasma) or psoriatic intertrigos (flexural psoriasis) may sometimes explain the failure of therapy.

摘要

在大多数情况下,与胃肠道疾病相关的肛门皮肤临床症状并不具有特异性(红斑、瘙痒、伤口或瘢痕形成)。然而,在以下疾病中,偶尔出现的皮肤病变可能直接有助于诊断:在克罗恩病、肠道结核、慢性阿米巴病和血吸虫病中,肛门区域的皮肤病变与肠道病变具有相同的组织结构。肛周瘘管和溃疡在克罗恩病中很常见,尤其是在结肠和直肠有扩散的情况下;它们对类固醇治疗反应不佳,且常与较差的预后相关。肛周特异性病变常发生于儿童蛲虫病、消化道念珠菌病、系统性口疮病以及某些恶性肿瘤中。在其他胃肠道疾病中,皮肤表现的特异性较低,仅具有提示作用:医源性和微生物性腹泻、泻药的副作用、直肠疾病。必须强调的是,只有当更深层的病变扩散到肛周皮肤时才会引起肛门瘙痒。在直肠科实践中,对麻醉剂或栓剂香脂(秘鲁香脂)过敏引起的接触性皮炎、局部滥用类固醇导致的瘙痒或烧灼性萎缩、未确诊的真菌(念珠菌病)、细菌(红癣)或银屑病性擦烂(屈侧银屑病)有时可能解释治疗失败的原因。

相似文献

1
[Anal symptoms of gastro-intestinal diseases].[胃肠疾病的肛门症状]
Ann Dermatol Venereol. 1979 Jan;106(1):25-30.
2
Perianal disease in children and adolescents with Crohn's disease.患有克罗恩病的儿童和青少年的肛周疾病
Gastroenterology. 1984 May;86(5 Pt 1):829-33.
3
[Surgical management of perianal lesions in Crohn's disease].[克罗恩病肛周病变的外科治疗]
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4
Cyclosporin treatment of anal and perianal lesions associated with Crohn's disease.
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5
Prior bowel resections, perianal disease, and a high initial Crohn's disease activity index are associated with corticosteroid resistance in active Crohn's disease.既往肠道切除术、肛周疾病以及较高的初始克罗恩病活动指数与活动性克罗恩病患者的皮质类固醇抵抗相关。
Am J Gastroenterol. 2002 Jun;97(6):1438-45. doi: 10.1111/j.1572-0241.2002.05685.x.
6
[Anal and perianal lesions in Crohn's disease].
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[Perianal complications of Crohn disease].[克罗恩病的肛周并发症]
Acta Chir Iugosl. 2000;47(1-2):67-70.
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Perianal Crohn's disease.肛周克罗恩病
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Perianal Crohn's disease: classification and clinical evaluation.肛周克罗恩病:分类与临床评估
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10
[Anal and perianal operations in ulcerative colitis and Crohn's disease].[溃疡性结肠炎和克罗恩病的肛门及肛周手术]
Schweiz Med Wochenschr. 1988 May 21;118(20):749-55.