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大鼠肿瘤同种异体移植引发过敏抗体反应。

Rat tumour allografts evoke anaphylactic antibody responses.

作者信息

Broom B C, Alexander P

出版信息

Immunology. 1975 Jun;28(6):1033-40.

Abstract

In vitro assays of release of histamine from peritoneal mast cells showed that Wistar rats produced anaphylactic antibody in response to a single immunization with an allogeneic sarcoma. The response occurs early after immunization, and no adjuvant is needed. The thermolability of the anaphylactic antibody suggests that it is IgE.

摘要

对腹膜肥大细胞组胺释放的体外测定表明,Wistar大鼠对同种异体肉瘤单次免疫会产生过敏抗体。该反应在免疫后早期出现,且无需佐剂。过敏抗体的热不稳定性表明它是IgE。

引用本文的文献

1
Atopy--a favourable prognostic factor for survival in Hodgkin's disease.
Br J Cancer. 1983 Aug;48(2):209-15. doi: 10.1038/bjc.1983.176.
2
Tumor-reactive IgE antibodies in plasma of patients with gastrointestinal carcinomas.
Cancer Immunol Immunother. 1983;14(3):180-4. doi: 10.1007/BF00205357.
3
Mast cell modulation of tumour cell proliferation in rat mammary adenocarcinoma 13762NF.
Br J Cancer. 1991 Jun;63(6):873-8. doi: 10.1038/bjc.1991.192.

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