福氏耐格里阿米巴菌株HB-1对选定抗菌药物的单独及联合体外敏感性。
In vitro susceptibilities of Naegleria fowleri strain HB-1 to selected antimicrobial agents, singly and in combination.
作者信息
Lee K K, Karr S L, Wong M M, Hoeprich P D
出版信息
Antimicrob Agents Chemother. 1979 Aug;16(2):217-20. doi: 10.1128/AAC.16.2.217.
Abstract
The overall prognosis of primary amoebic meningoencephalitis remains poor. The results of this study support previous finding that amphotericin B is the most efficacious drug against the Naegleria species in in vitro testing. In addition, the methyl ester of amphotericin B, a new derivative, also appears to be an effective agent. Of the drug combinations studied, amphotericin B plus minocycline and amphotericin B plus tetracycline showed synergy. The clinical significance of these findings remains to be determined.
摘要
原发性阿米巴脑膜脑炎的总体预后仍然很差。本研究结果支持先前的发现，即两性霉素B在体外试验中是对抗耐格里属物种最有效的药物。此外，两性霉素B的甲酯，一种新的衍生物，似乎也是一种有效的药物。在所研究的药物组合中，两性霉素B加米诺环素和两性霉素B加四环素显示出协同作用。这些发现的临床意义仍有待确定。
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Antimicrob Agents Chemother. 1979 Aug;16(2):217-20. doi: 10.1128/AAC.16.2.217.
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本文引用的文献
1
RELEASE OF INTRACELLULAR CONSTITUENTS OF CANDIDA ALBICANS IN PRESENCE OF POLYENE ANTIBIOTICS.在多烯抗生素存在的情况下白色念珠菌细胞内成分的释放
Ann Biochem Exp Med. 1963 Dec;23:611-26.
2
Sensitivity to amphotericin B of a Naegleria sp. isolated from a case of primary amoebic meningoencephalitis.从一例原发性阿米巴脑膜脑炎病例中分离出的一种耐格里属变形虫对两性霉素B的敏感性。
J Clin Pathol. 1969 Jul;22(4):470-4. doi: 10.1136/jcp.22.4.470.
3
Primary amoebic meningoencephalitis in Britain.英国的原发性阿米巴脑膜脑炎
Br Med J. 1970 Mar 7;1(5696):596-9. doi: 10.1136/bmj.1.5696.596.
4
Small, free-living amebas: cultivation, quantitation, identification, classification, pathogenesis, and resistance.小型自由生活阿米巴：培养、定量、鉴定、分类、发病机制及耐药性
Curr Top Comp Pathobiol. 1971;1:201-54. doi: 10.1016/b978-0-12-153401-1.50010-7.
5
Light and electron microsopic observations on the pathogenesis of Naegleria fowleri in mouse brain and tissue culture.对福氏耐格里阿米巴在小鼠脑和组织培养中的发病机制的光镜和电镜观察。
J Protozool. 1974 May;21(2):239-50. doi: 10.1111/j.1550-7408.1974.tb03648.x.
6
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Am Rev Respir Dis. 1974 Nov;110(5):671-3. doi: 10.1164/arrd.1974.110.5.671.
7
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