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与吸收不良相关的贾第虫病中的血清抗体和空肠组织学

Serum antibodies and jejunal histology in giardiasis associated with malabsorption.

作者信息

Ridley M J, Ridley D S

出版信息

J Clin Pathol. 1976 Jan;29(1):30-4. doi: 10.1136/jcp.29.1.30.

Abstract

An immunofluorescent test, using Giardia lamblia cysts as antigen, gave positive results in 32/36 cases of giardiasis with malabsorption, 0/2 cases of giardiasis without malabsorption, and 0/17 control patients without giardiasis or malabsorption. The test was positive in 10/34 patients with malabsorption in whom G. lamblia could not be detected by stool examination or biopsy; some of these cases were presumed to be cryptic giardiasis. There was a crude correlation between antibody titre and the severity of the histological lesion in the jejunum. The finding of a reliable source of antigen remains a problem.

摘要

一项以蓝氏贾第鞭毛虫包囊作为抗原的免疫荧光试验,在36例伴有吸收不良的贾第虫病患者中有32例呈阳性结果,2例无吸收不良的贾第虫病患者结果为阴性,17例无贾第虫病或吸收不良的对照患者结果也为阴性。在34例粪便检查或活检未检测到蓝氏贾第鞭毛虫的吸收不良患者中,有10例试验呈阳性;其中一些病例被推测为隐匿性贾第虫病。抗体滴度与空肠组织学病变的严重程度之间存在粗略的相关性。找到可靠的抗原来源仍然是一个问题。

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