Manuel P D, Kilby A, Candy D, Walker-Smith J A, Harries J T
Arch Dis Child. 1978 Aug;53(8):642-4. doi: 10.1136/adc.53.8.642.
Three children aged between 7 and 11 years, after an acute onset of diarrhoea and vomiting, developed protracted diarrhoea and severe loss of weight. None had been abroad. No significant aetiological agent was found. There was evidence of acute inflammatory disease on proximal small intestinal biopsy, and some evidence of more widespread gut involvement--of the rectum in Cases 1 and 2, and the terminal ileum in Cases 2 and 3. The disease resolved spontaneously and without relapse.
三名年龄在7至11岁之间的儿童,在急性腹泻和呕吐发作后,出现了迁延性腹泻和严重体重减轻。他们都未曾出过国。未发现明显的病原体。近端小肠活检有急性炎症性疾病的证据,还有一些证据表明肠道受累范围更广——病例1和病例2的直肠,以及病例2和病例3的回肠末端。疾病自行缓解且未复发。