Rossi C R, Kiesel G K
Infect Immun. 1974 Aug;10(2):293-8. doi: 10.1128/iai.10.2.293-298.1974.
A serological investigation for neutralizing antibody to bovine respiratory syncytial virus (BRSV) was conducted using an antigenically related human strain of respiratory syncytial virus. Results demonstrated the effectiveness of the procedure. Sixty-seven percent of healthy, adult cattle tested were found to have antibody to BRSV. Calves in several herds were exposed to conditions to encourage development of respiratory tract disease. In three herds in which respiratory tract disease subsequently developed, the incidence of BRSV seroconversions approached 100%. In a herd in which no respiratory tract disease was detected, BRSV seroconversions indicated a high incidence of subclinical infections. It was concluded that, in this country as has been shown in others, BRSV is probably a significant pathogen of the bovine respiratory tract.
使用与呼吸道合胞病毒抗原相关的人类毒株,对牛呼吸道合胞病毒(BRSV)中和抗体进行了血清学调查。结果证明了该方法的有效性。检测的健康成年牛中有67%被发现具有BRSV抗体。几个牛群中的犊牛暴露于促使呼吸道疾病发展的环境中。在随后发生呼吸道疾病的三个牛群中,BRSV血清转化的发生率接近100%。在一个未检测到呼吸道疾病的牛群中,BRSV血清转化表明亚临床感染的发生率很高。得出的结论是,正如在其他国家所显示的那样,在这个国家,BRSV可能是牛呼吸道的一种重要病原体。