Fedrick J
Br J Prev Soc Med. 1974 May;28(2):93-7. doi: 10.1136/jech.28.2.93.
Of the 206 cases of sudden unexpected death in infancy (SUD) 170 were linked with the maternity information and birth certificates on the Oxford Record Linkage files. Statistically highly significant correlations were demonstrated with low maternal age, high parity, and low social class, the last two associations being more marked among the mothers of infants who died after the 12th week. Each case of SUD was then matched with three control livebirths for maternal age, parity, civil state of mother, social class, year and hospital of delivery, and as closely as possible for area of residence. A comparison of mothers of cases with those of the controls revealed a highly significant preponderance of women who were born outside the area, and no significant effect with maternal religion, previous pregnancy loss, or ABO blood group. Other pregnancies occurring to the case and control mothers between 1965 and 1971 were also traced. It was shown that the infant dying an SUD was more likely to have been conceived within six months of the birth of his preceding sib.
在206例婴儿猝死(SUD)病例中,有170例与牛津记录链接文件中的产妇信息和出生证明相关。研究表明,产妇年龄小、多胎妊娠和社会阶层低与婴儿猝死存在统计学上的高度显著相关性,后两种关联在第12周后死亡婴儿的母亲中更为明显。然后,将每例婴儿猝死病例与三个存活对照出生病例进行匹配,匹配因素包括产妇年龄、胎次、母亲婚姻状况、社会阶层、分娩年份和医院,并尽可能匹配居住地区。对病例组母亲和对照组母亲进行比较发现,出生在该地区以外的女性占比极高,而母亲的宗教信仰、既往流产史或ABO血型则无显著影响。还追踪了病例组和对照组母亲在1965年至1971年间的其他妊娠情况。结果显示,死于婴儿猝死的婴儿更有可能是在其前一个同胞出生后六个月内受孕的。